Bacteriocin: staphylococcin C55 alpha

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Bacteriocin: staphylococcin C55 alpha

Accession: BAC194

Classification
Genetics
Gene: ORFNames=SAP057A_040
Producer and target organisms

Producer Organism: Staphylococcus aureus [Gram-positive]

Taxonomy: BacteriaFirmicutesBacillalesStaphylococcus

Target organismsUnavailable data

Uniprot and PDB links

UniProt Entry: Q9S4D3

PDB EntryUnknown

NUCLEOTIDE SEQUENCE, STRAIN=C55.
MEDLINE=99346225;PubMed=10417203;
Navaratna M.A., Sahl H.G., Tagg J.R.
"Identification of genes encoding two-component lantibiotic production in Staphylococcus aureus C55 and other phage group II S. aureus strains and demonstration of an association with the exfoliative toxin B gene.", Infect. Immun. 67:4268-4271(1999).
NUCLEOTIDE SEQUENCE, STRAIN=C55.
Navaratna M.A.D.B., Tagg J.R., Sahl H.-G.
"", Submitted (MAY-1999) to the EMBL/GenBank/DDBJ databases.
NUCLEOTIDE SEQUENCE, STRAIN=3049; PLASMID=SAP057A.
Gill J., Borman J., Shetty J., Hostetler J., Durkin S., Montgomery B.
"", Submitted (AUG-2009) to the EMBL/GenBank/DDBJ databases.
NUCLEOTIDE SEQUENCE, STRAIN=3049; PLASMID=SAP057A.
Summers A.O., Shearer J., Wireman J.
"", Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases.
NUCLEOTIDE SEQUENCE, STRAIN=TY4; PLASMID=ETB plasmid.
MEDLINE=21562640;PubMed=11705958;DOI=10.1128/IAI.69.12.7760-7771.2001
Yamaguchi T., Hayashi T., Takami H., Ohnishi M., Murata T., Nakayama K., Asakawa K., Ohara M., Komatsuzawa H., Sugai M.
"Complete nucleotide sequence of a Staphylococcus aureus exfoliative toxin B plasmid and identification of a novel ADP-ribosyltransferase, EDIN-C.", Infect. Immun. 69:7760-7771(2001).
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Protein sequence
 ........10 ........20 ........30 ........40 
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 CSTNTFSLSD YWGNKGNWCT ATHECMSWCK

Wheel representation
wheel representation of staphylococcin C55 alpha
Composition
Hydrophobicity

Composition
Formula C0 H0 N0 O0 S0
Absent amino acids IPQRV
Common amino acids STC
Mass (Da) 3
Net charge +1
Isoelectric point 7.12
Basic residues 3
Acidic residues 2
Hydrophobic residues 6
Polar residues 18
Aliphatic residues 1
Tiny residues 7
Boman Index -49.18
Hydropathy Index -0.633
Aliphatic Index 16.33
Instability Index 46 (unstable)
Half Life Mammalian : 1.2 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 18240 M-1 cm-1
Absorbance 280nm 628.97

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