Bacteriocin: Circularin A
Accession: BAC164
Classification
Class: Unclassified
Genetics
Gene: GK0719
Producer and target organisms
Producer Organism: Geobacillus kaustophilus [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Bacillales
Bacillaceae
Geobacillus
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: Q5L226
PDB EntryUnknown
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].STRAIN=HTA426
PubMed=15576355;DOI=10.1093/nar/gkh970
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
"Thermoadaptation trait revealed by the genome sequence ofthermophilic Geobacillus kaustophilus", Nucleic Acids Res. 32:6292-6303(2004
PubMed=15576355;DOI=10.1093/nar/gkh970
Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H., Matsui S., Uchiyama I.
"Thermoadaptation trait revealed by the genome sequence ofthermophilic Geobacillus kaustophilus", Nucleic Acids Res. 32:6292-6303(2004
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Protein sequence
| ........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 | | | | | | | | MSLLALVAGT LGVSQSIATT VVSIVLTGST LISIILGITA ILSGGVDAIL EIGWSAFVAT VKKIVAERGK AAAIAW |
Wheel representation
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 12 | 15.79 % |
| C | 0 | 0.00 % |
| D | 1 | 1.32 % |
| E | 2 | 2.63 % |
| F | 1 | 1.32 % |
| G | 8 | 10.53 % |
| H | 0 | 0.00 % |
| I | 11 | 14.47 % |
| K | 3 | 3.95 % |
| L | 9 | 11.84 % |
| M | 1 | 1.32 % |
| N | 0 | 0.00 % |
| P | 0 | 0.00 % |
| Q | 1 | 1.32 % |
| R | 1 | 1.32 % |
| S | 8 | 10.53 % |
| T | 7 | 9.21 % |
| V | 9 | 11.84 % |
| W | 2 | 2.63 % |
| Y | 0 | 0.00 % |
Hydrophobicity
Composition
| Formula | C348
H589
N85
O99
S1 |
| Absent amino acids | CHNPY |
| Common amino acids | AI |
| Mass (Da) | 7599.42 |
| Net charge | +1 |
| Isoelectric point | 9.44 |
| Basic residues | 4 |
| Acidic residues | 3 |
| Hydrophobic residues | 44 |
| Polar residues | 23 |
| Aliphatic residues | 29 |
| Tiny residues | 28 |
| Boman Index | 69.35 |
| Hydropathy Index | 1.33 |
| Aliphatic Index | 152.76 |
| Instability Index | 26.06 (stable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 11000 M-1 cm-1 |
| Absorbance 280nm | 146.67 |
