Durancin Q

Accession: BAC160

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Bacteriocin: Durancin Q

Accession: BAC160
Classification
Class: Unclassified
Genetics
Gene: duqQ
Producer and target organisms

Producer Organism: Enterococcus durans [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus

Target organismsUnavailable data

Uniprot and PDB links

UniProt Entry: B5BP43

PDB EntryUnknown

[Ref. 1]
NUCLEOTIDE SEQUENCE.STRAIN=QU 21
Hu C., Zendo T., Nakayama J., Sonomoto K.
"Purification and genetic characterization of bacteriocins produced by Enterococcus durans QU 21.", Submitted (MAR-2007) to the EMBL/GenBank/DDBJ database
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Gene structure
genome of Durancin Q

Gene idNameDescriptionLocation
BACGene742cdaCDA cytosine deaminase cytosine deaminase homologuecomplement(1..407)
BACGene743duqIDuqI immunity protein of durancin Q571..816
BACGene744duqQprepeptide of durancin Q DuqQ; non-pediocin-like Class II bacteriocin with double-glycine type leadersequencecomplement(1008..1226)
BACGene745duqFDuqF prepeptide of durancin Q inducing peptide with double-glycine type leadersequence1456..1581
BACGene746duqKDuqK putative; histidine protein kinase homologue1624..2919
BACGene747duqRDuqR putative; response regulator homologue2930..3676
BACGene748duqRDx Dx region; no putative RBS; simlar with C-terminal part of accessory protein ofbacteriocin-related ABC transporter system3868..4518
BACGene749imsIMS ImpB/MucB/SamB family protein putative; ImpB/MucB/SamB family protein4776..5118
cdaduqIduqQduqFduqKduqRduqRims
Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 
          |          |          |          |          |          |          |          | 
 MQTIKELNTM ELQEIIGGEN DHRMPYELNR PNNLSKGGAK CAAGILGAGL GAVGGGPGGF ISAGISAVLG CM

warming sequence of prepeptide
Wheel representation
wheel representation of Durancin Q
Composition
Amino acidCountPercent
A79.72 %
C22.78 %
D11.39 %
E56.94 %
F11.39 %
G1520.83 %
H11.39 %
I68.33 %
K34.17 %
L79.72 %
M45.56 %
N56.94 %
P34.17 %
Q22.78 %
R22.78 %
S34.17 %
T22.78 %
V22.78 %
W00.00 %
Y11.39 %
Hydrophobicity

Composition
Formula C310 H510 N90 O98 S6
Absent amino acids W
Common amino acids G
Mass (Da) 7277.62
Net charge 0
Isoelectric point 5.71
Basic residues 6
Acidic residues 6
Hydrophobic residues 23
Polar residues 28
Aliphatic residues 15
Tiny residues 25
Boman Index -39.93
Hydropathy Index 0.07
Aliphatic Index 88.19
Instability Index 30.53 (stable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 1490 M-1 cm-1
Absorbance 280nm 22.75