Nisin F

Accession: BAC146

Default view

Bacteriocin: Nisin F

Accession: BAC146

Classification

Class: Lantibiotic

Genetics

Gene: BacF

Producer and target organisms

Producer Organism: Lactococcus lactis F10 [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesStreptococcaceaeLactococcus

Target organismsStaphylococcus aureus - Staphylococcus carnosus - Lactobacillus curvatus - Lactobacillus plantarum - Lactobacillus reuteri

Description

under review

Related Entries

Nisin A Nisin Z Nisin Q nisin U

Uniprot and PDB links

UniProt Entry: A7UGI5

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

GENE SEQUENCEE
PubMed=18039827;DOI=10.1128/AEM.01862-07
de Kwaadsteniet M, Ten Doeschate K, Dicks L M T.
"Characterization of the Structural Gene Encoding Nisin F, a New Lantibiotic Produced by a Lactococcus lactis subsp. lactis Isolate from Freshwater Catfish (Clarias gariepinus)", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2008, 74(2):547-549.

Gene structure

Gene id	Name	Description	Location
BACGene653		nisin F	1..171

Protein sequence

........10 ........20 ........30 ........40
| | | |
ITSISLCTPG CKTGALMGCN MKTATCNCSV HVSK

Wheel representation

Composition

Amino acid	Count	Percent
A	2	5.88 %
C	5	14.71 %
D	0	0.00 %
E	0	0.00 %
F	0	0.00 %
G	3	8.82 %
H	1	2.94 %
I	2	5.88 %
K	3	8.82 %
L	2	5.88 %
M	2	5.88 %
N	2	5.88 %
P	1	2.94 %
Q	0	0.00 %
R	0	0.00 %
S	4	11.76 %
T	5	14.71 %
V	2	5.88 %
W	0	0.00 %
Y	0	0.00 %

Hydrophobicity

Composition

Formula	C₁₄₀ H₂₄₃ N₄₁ O₄₆ S₇
Absent amino acids	DEFQRWY
Common amino acids	CT
Mass (Da)	3479.71
Net charge	+4
Isoelectric point	8.51
Basic residues	4
Acidic residues	0
Hydrophobic residues	8
Polar residues	19
Aliphatic residues	6
Tiny residues	9
Boman Index	-15.74
Hydropathy Index	0.4
Aliphatic Index	68.82
Instability Index	13.45 (stable)
Half Life	Mammalian : 20 hour Yeast : 30 min E. coli : >10 hour
Extinction Coefficient	0 M^-1 cm^-1
Absorbance 280nm	7.58