Lactococcin-G α

Accession: BAC129

Default view

Bacteriocin: lactococcin-G α

Accession: BAC129

Classification

Class: ~~Unclassified~~

Genetics

Gene: ~~Unidentified~~

Producer and target organisms

Producer Organism: Lactococcus lactis subsp. lactis (Streptococcus lactis) [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesStreptococcaceaeLactococcus

Target organisms~~Unavailable data~~

Uniprot and PDB links

UniProt Entry: P36961

PDB Entry2JPJ resolved by NMR 2JPL resolved by NMR

[Ref. 1] | View abstract | Export citation

PROTEIN SEQUENCE.STRAIN=LMG 2081
MEDLINE=92380946;PubMed=1512201;
Nissen-Meyer J., Holo H., Havarstein L.S., Sletten K., Nes I.F.
"A novel lactococcal bacteriocin whose activity depends on thecomplementary action of two peptides.", J. Bacteriol. 174:5686-5692(1992)

Protein sequence

........10 ........20 ........30 ........40
| | | |
GTWDDIGQGI GRVAYWVGKA MGNMSDVNQA SRINRKKKH

Wheel representation

3D Structure

View PDB entry: 2JPJ

Protein sequence annotations

Feature	Position(s)	Length	Description
PEPTIDE	1↔39	39	Bacteriocin lactococcin-G subunit alpha. Feature identifier = PRO_0000044640.
HELIX	3↔21	19
HELIX	26↔34	9
HELIX	35↔37	3

Composition

Amino acid	Count	Percent
A	3	7.69 %
C	0	0.00 %
D	3	7.69 %
E	0	0.00 %
F	0	0.00 %
G	6	15.38 %
H	1	2.56 %
I	3	7.69 %
K	4	10.26 %
L	0	0.00 %
M	2	5.13 %
N	3	7.69 %
P	0	0.00 %
Q	2	5.13 %
R	3	7.69 %
S	2	5.13 %
T	1	2.56 %
V	3	7.69 %
W	2	5.13 %
Y	1	2.56 %

Hydrophobicity

Composition

Formula	C₁₈₇ H₂₉₉ N₆₁ O₅₅ S₂
Absent amino acids	CEFLP
Common amino acids	G
Mass (Da)	4364.59
Net charge	+5
Isoelectric point	10.84
Basic residues	8
Acidic residues	3
Hydrophobic residues	11
Polar residues	13
Aliphatic residues	6
Tiny residues	11
Boman Index	-90.98
Hydropathy Index	-0.84
Aliphatic Index	60
Instability Index	4.44 (stable)
Half Life	Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour
Extinction Coefficient	12490 M^-1 cm^-1
Absorbance 280nm	328.68