Cerein 7B

Accession: BAC128

Default view

Bacteriocin: cerein 7B

Accession: BAC128

Classification

Class: ~~Unclassified~~

Genetics

Gene: CER7B

Producer and target organisms

Producer Organism: Bacillus cereus Bc7 (CECT 5148) [Gram-positive]

Taxonomy: BacteriaFirmicutesBacillalesBacillaceaeBacillus

Target organismsactive against Micrococcus luteus ATCC 7468 - Listeria innocua G244 -

Inactive against Staphylococcus aureus ATCC 12600

Uniprot and PDB links

UniProt Entry: Q2MDB2

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=Bc7
PubMed=16451187;DOI=10.1111/j.1574-6968.2005.00009.x
Oscariz, J., Cintas, L., Holo, H., Lasa, I., Nes, I.F., Pisabarro, A.G.
"Purification and sequencing of cerein 7B, a novel bacteriocin produced by Bacillus cereus Bc7.", (2006) FEMS Microbiol. Lett. 254:108-115.

Gene structure

Gene id	Name	Description	Location
BACGene587	cer7B	bacteriocin cerein 7B precursor	137..361

Protein sequence

........10 ........20 ........30 ........40 ........50 ........60
| | | | | |
GWWNSWGKCV AGTIGGAGTG GLGGAAAGSA VPVIGTGIGG AIGGVSGGLT GAATFC

Wheel representation

Protein sequence annotations

Feature	Position(s)	Length	Description
CHAIN	1↔56	56	bacteriocin cerein 7B. Feature identifier = PRO_5000076738.

Composition

Amino acid	Count	Percent
A	9	16.07 %
C	2	3.57 %
D	0	0.00 %
E	0	0.00 %
F	1	1.79 %
G	20	35.71 %
H	0	0.00 %
I	4	7.14 %
K	1	1.79 %
L	2	3.57 %
M	0	0.00 %
N	1	1.79 %
P	1	1.79 %
Q	0	0.00 %
R	0	0.00 %
S	3	5.36 %
T	5	8.93 %
V	4	7.14 %
W	3	5.36 %
Y	0	0.00 %

Hydrophobicity

Composition

Formula	C₂₁₅ H₃₃₃ N₆₁ O₆₆ S₂
Absent amino acids	DEHMQRY
Common amino acids	G
Mass (Da)	4892.81
Net charge	+1
Isoelectric point	8.23
Basic residues	1
Acidic residues	0
Hydrophobic residues	23
Polar residues	31
Aliphatic residues	10
Tiny residues	32
Boman Index	58.06
Hydropathy Index	0.729
Aliphatic Index	17.62
Instability Index	15.14 (stable)
Half Life	Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour
Extinction Coefficient	16625 M^-1 cm^-1
Absorbance 280nm	302.27