Penocin A

Accession: BAC124

Default view

Bacteriocin: Penocin A

Accession: BAC124

Classification

Class: class IIA/YGNGV

Genetics

Gene: PenA

Producer and target organisms

Producer Organism: Pediococcus pentosaceus ATCC 25745 [Gram-positive]

Taxonomy: BacteriaFirmicutesBacilliLactobacillalesLactobacillaceaePediococcus.

Target organismsCarnobacterium piscicola - Clostridia butyricum - Enterococcus faecium - Enterococcus faecalis - Lactobacillus curvatus - Lactobacillus casei - Lactobacillus sakei - Lactococcus raffinolactis - Leuconostoc mesenteroides - Listeria innocua - Listeria monocytogenes - Pediococcus acidilactici - Pediococcus pentosaceus

Uniprot and PDB links

UniProt Entry: Q03HX9

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

PROTEIN SEQUENCE, STRAIN=ATCC 25745
PubMed=16735728;DOI=10.1099/mic.0.28794-0
Diep DB, Godager L, Brede D, Nes IF.
"Data mining and characterization of a novel pediocin-like bacteriocin system from the genome of Pediococcus pentosaceus ATCC 25745.", Microbiology. 2006 Jun;152(Pt 6):1649-59.

Protein sequence

........10 ........20 ........30 ........40 ........50
| | | | |
KYYGNGVHCG KKTCYVDWGQ ATASIGKIIV NGWTQHGPWA HR

Wheel representation

Composition

Amino acid	Count	Percent
A	3	7.14 %
C	2	4.76 %
D	1	2.38 %
E	0	0.00 %
F	0	0.00 %
G	7	16.67 %
H	3	7.14 %
I	3	7.14 %
K	4	9.52 %
L	0	0.00 %
M	0	0.00 %
N	2	4.76 %
P	1	2.38 %
Q	2	4.76 %
R	1	2.38 %
S	1	2.38 %
T	3	7.14 %
V	3	7.14 %
W	3	7.14 %
Y	3	7.14 %

Hydrophobicity

Composition

Formula	C₂₁₂ H₃₁₂ N₆₂ O₅₆ S₂
Absent amino acids	EFLM
Common amino acids	G
Mass (Da)	4684.6
Net charge	+7
Isoelectric point	9.45
Basic residues	8
Acidic residues	1
Hydrophobic residues	12
Polar residues	18
Aliphatic residues	6
Tiny residues	11
Boman Index	-47.27
Hydropathy Index	-0.586
Aliphatic Index	7.93
Instability Index	-23.82 (stable)
Half Life	Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min
Extinction Coefficient	21095 M^-1 cm^-1
Absorbance 280nm	514.51