Propionicin T1

Accession: BAC123

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Bacteriocin: Propionicin T1

Accession: BAC123
Classification
Class: Unclassified
Genetics
Gene: pctA
Producer and target organisms

Producer Organism: Propionibacterium thoenii [Gram-positive]

Taxonomy: BacteriaActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium

Target organismsUnavailable data

Uniprot and PDB links

UniProt Entry: Q9F6C4

PDB EntryUnknown

[Ref. 1] | View abstract | Export citation
NUCLEOTIDE SEQUENCE.
MEDLINE=20466828;PubMed=11010864;DOI=10.1128/AEM.66.10.4230-4236.2000
Faye T., Langsrud T., Nes I.F., Holo H.
"Biochemical and genetic characterization of propionicin T1, a new bacteriocin from Propionibacterium thoenii.", Appl. Environ. Microbiol. 66:4230-4236(2000).
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Gene structure
genome of Propionicin T1

Gene idNameDescriptionLocation
BACGene582pctApropionicin T1 PctA292..582
BACGene583pctAputative ABC transporter Orf2647..1921
pctApctA
Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 ........70 
          |          |          |          |          |          |          | 
 VPGGCTYTRS NRDVIGTCKT GSGQFRIRLD CNNAPDKTSV WAKPKVMVSV HCLVGQPRSI SFETK
Wheel representation
wheel representation of Propionicin T1
Composition
Amino acidCountPercent
A23.08 %
C46.15 %
D34.62 %
E11.54 %
F23.08 %
G69.23 %
H11.54 %
I34.62 %
K57.69 %
L23.08 %
M11.54 %
N34.62 %
P46.15 %
Q23.08 %
R57.69 %
S69.23 %
T69.23 %
V710.77 %
W11.54 %
Y11.54 %
Hydrophobicity

Composition
Formula C305 H497 N93 O92 S5
Absent amino acids -
Common amino acids VGST
Mass (Da) 7118.23
Net charge +7
Isoelectric point 10.01
Basic residues 11
Acidic residues 4
Hydrophobic residues 17
Polar residues 26
Aliphatic residues 12
Tiny residues 14
Boman Index -129.04
Hydropathy Index -0.386
Aliphatic Index 3.72
Instability Index 27.34 (stable)
Half Life Mammalian : 100 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 7240 M-1 cm-1
Absorbance 280nm 113.13