Gassericin A

Accession: BAC121

Default view

Bacteriocin: Gassericin A

Accession: BAC121

Classification

Class: ~~Unclassified~~

Genetics

Gene: gaaA

Producer and target organisms

Producer Organism: Lactobacillus gasseri [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organisms~~Unavailable data~~

Uniprot and PDB links

UniProt Entry: O24790

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=LA39
MEDLINE=98312025;PubMed=9648219;
Kawai Y., Saito T., Suzuki M., Itoh T.
"Sequence analysis by cloning of the structural gene of gassericin A, a hydrophobic bacteriocin produced by Lactobacillus gasseri LA39.", Biosci. Biotechnol. Biochem. 62:887-892(1998).

[Ref. 2]

NUCLEOTIDE SEQUENCE
DOI=10.1006/fmic.2001.0412
Kawai, Y., Y. Ishii, K. Uemura, H. Kitazawa, T. Saito, and T. Itoh.
"Lactobacillus reuteri LA6 and Lactobacillus gasseri LA39 isolated from feces of the same human infant produce identical cyclic bacteriocin.", Food Microbiol. 18:407-415 (2001).

Protein sequence

........10 ........20 ........30 ........40 ........50 ........60
| | | | | |
IYWIADQFGI HLATGTARKL LDAMASGASL GTAFAAILGV TLPAWALAAA GALGATAA

Wheel representation

Composition

Amino acid	Count	Percent
A	18	31.03 %
C	0	0.00 %
D	2	3.45 %
E	0	0.00 %
F	2	3.45 %
G	7	12.07 %
H	1	1.72 %
I	4	6.90 %
K	1	1.72 %
L	8	13.79 %
M	1	1.72 %
N	0	0.00 %
P	1	1.72 %
Q	1	1.72 %
R	1	1.72 %
S	2	3.45 %
T	5	8.62 %
V	1	1.72 %
W	2	3.45 %
Y	1	1.72 %

Hydrophobicity

Composition

Formula	C₂₆₁ H₄₁₁ N₆₇ O₇₂ S₁
Absent amino acids	CEN
Common amino acids	A
Mass (Da)	5672.18
Net charge	+1
Isoelectric point	7.54
Basic residues	3
Acidic residues	2
Hydrophobic residues	35
Polar residues	15
Aliphatic residues	13
Tiny residues	27
Boman Index	47.31
Hydropathy Index	0.997
Aliphatic Index	31.62
Instability Index	3.73 (stable)
Half Life	Mammalian : 20 hour Yeast : 30 min E. coli : >10 hour
Extinction Coefficient	19490 M^-1 cm^-1
Absorbance 280nm	219.12