Bacteriocin: Listeriocin 743A
Accession: BAC116
Classification
Class: Class IIa
Genetics
Gene: lisA
Producer and target organisms
Producer Organism: Listeria innocua [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Bacillales
Listeriaceae
Listeria
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: Q9AGM4
PDB EntryUnknown
NUCLEOTIDE SEQUENCE.
MEDLINE=21417025;PubMed=11526003;DOI=10.1128/AEM.67.9.4041-4047.2001
Kalmokoff M.L., Banerjee S.K., Cyr T., Hefford M.A., Gleeson T.
"Identification of a new plasmid-encoded sec-dependent bacteriocin produced by Listeria innocua 743.", Appl. Environ. Microbiol. 67:4041-4047(2001).
MEDLINE=21417025;PubMed=11526003;DOI=10.1128/AEM.67.9.4041-4047.2001
Kalmokoff M.L., Banerjee S.K., Cyr T., Hefford M.A., Gleeson T.
"Identification of a new plasmid-encoded sec-dependent bacteriocin produced by Listeria innocua 743.", Appl. Environ. Microbiol. 67:4041-4047(2001).
Loading...
Gene structure
| Gene id | Name | Description | Location |
| BACGene533 | lisA | listeriocin 743A | 76..291 |
| BACGene534 | lisB | immunity protein start codon not identified | 305..688 |
Protein sequence
| ........10 ........20 ........30 ........40 ........50 | | | | | KSYGNGVQCN KKKCWVDWGS AISTIGNNSA ANWATGGAAG WKS |
Wheel representation
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 6 | 13.95 % |
| C | 2 | 4.65 % |
| D | 1 | 2.33 % |
| E | 0 | 0.00 % |
| F | 0 | 0.00 % |
| G | 7 | 16.28 % |
| H | 0 | 0.00 % |
| I | 2 | 4.65 % |
| K | 5 | 11.63 % |
| L | 0 | 0.00 % |
| M | 0 | 0.00 % |
| N | 5 | 11.63 % |
| P | 0 | 0.00 % |
| Q | 1 | 2.33 % |
| R | 0 | 0.00 % |
| S | 5 | 11.63 % |
| T | 2 | 4.65 % |
| V | 2 | 4.65 % |
| W | 4 | 9.30 % |
| Y | 1 | 2.33 % |
Hydrophobicity
Composition
| Formula | C195
H294
N58
O60
S2 |
| Absent amino acids | EFHLMPR |
| Common amino acids | G |
| Mass (Da) | 4493.68 |
| Net charge | +4 |
| Isoelectric point | 9.99 |
| Basic residues | 5 |
| Acidic residues | 1 |
| Hydrophobic residues | 14 |
| Polar residues | 22 |
| Aliphatic residues | 4 |
| Tiny residues | 18 |
| Boman Index | -50.25 |
| Hydropathy Index | -0.556 |
| Aliphatic Index | 14.93 |
| Instability Index | -2.39 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 23615 M-1 cm-1 |
| Absorbance 280nm | 562.26 |
