Bacteriocin: Mundticin KS
Accession: BAC096
Classification
Class: Unclassified
Genetics
Gene: munA
Producer and target organisms
Producer Organism: Enterococcus mundtii [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Lactobacillales
Enterococcaceae
Enterococcus
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: Q8RR65
PDB EntryUnknown
NUCLEOTIDE SEQUENCE, STRAIN=NFRI 7393
MEDLINE=22142023;PubMed=12147478;DOI=10.1128/AEM.68.8.3830-3840.2002
Kawamoto S., Shima J., Sato R., Eguchi T., Ohmomo S., Shibato J., Horikoshi N., Takeshita K., Sameshima T.
"Biochemical and genetic characterization of mundticin KS, an antilisterial peptide produced by Enterococcus mundtii NFRI 7393.", Appl. Environ. Microbiol. 68:3830-3840(2002).
MEDLINE=22142023;PubMed=12147478;DOI=10.1128/AEM.68.8.3830-3840.2002
Kawamoto S., Shima J., Sato R., Eguchi T., Ohmomo S., Shibato J., Horikoshi N., Takeshita K., Sameshima T.
"Biochemical and genetic characterization of mundticin KS, an antilisterial peptide produced by Enterococcus mundtii NFRI 7393.", Appl. Environ. Microbiol. 68:3830-3840(2002).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene389 | munA | mundticin KS precursor bacteriocin | 1800..1952 |
| BACGene390 | munB | ATP-dependent transporter translocation and processing of mundticin KS | 2094..4118 |
| BACGene391 | munC | mundticin KS immunity protein | 4143..4439 |
Protein sequence
| ........10 ........20 ........30 ........40 ........50 | | | | | KYYGNGVSCN KKGCSVDWGK AIGIIGNNSA ANLATGGAAG WKS |
Wheel representation
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 6 | 13.95 % |
| C | 2 | 4.65 % |
| D | 1 | 2.33 % |
| E | 0 | 0.00 % |
| F | 0 | 0.00 % |
| G | 9 | 20.93 % |
| H | 0 | 0.00 % |
| I | 3 | 6.98 % |
| K | 5 | 11.63 % |
| L | 1 | 2.33 % |
| M | 0 | 0.00 % |
| N | 5 | 11.63 % |
| P | 0 | 0.00 % |
| Q | 0 | 0.00 % |
| R | 0 | 0.00 % |
| S | 4 | 9.30 % |
| T | 1 | 2.33 % |
| V | 2 | 4.65 % |
| W | 2 | 4.65 % |
| Y | 2 | 4.65 % |
Hydrophobicity
Composition
| Formula | C213
H337
N63
O67
S3 |
| Absent amino acids | EFHPR |
| Common amino acids | G |
| Mass (Da) | 4967.44 |
| Net charge | +4 |
| Isoelectric point | 9.81 |
| Basic residues | 5 |
| Acidic residues | 1 |
| Hydrophobic residues | 16 |
| Polar residues | 26 |
| Aliphatic residues | 6 |
| Tiny residues | 19 |
| Boman Index | -28.45 |
| Hydropathy Index | -0.11 |
| Aliphatic Index | 66.4 |
| Instability Index | 16.99 (stable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 14105 M-1 cm-1 |
| Absorbance 280nm | 287.86 |
