Plantaricin NC8 α

Accession: BAC089

Default view

Bacteriocin: Plantaricin NC8 α

Accession: BAC089

Classification

Class: ~~Unclassified~~

Genetics

Gene: plnc8A

Producer and target organisms

Producer Organism: Lactobacillus plantarum [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organisms~~Unavailable data~~

Uniprot and PDB links

UniProt Entry: Q84HW0

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=NC8
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).

[Ref. 2] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=NC8
MEDLINE=22401440;PubMed=12514019;DOI=10.1128/AEM.69.1.383-389.2003
Maldonado A., Ruiz-Barba J.L., Jimenez-Diaz R.
"Purification and genetic characterization of plantaricin NC8, a novel coculture-inducible two-peptide bacteriocin from Lactobacillus plantarum NC8.", Appl. Environ. Microbiol. 69:383-389(2003).

[Ref. 3]

NUCLEOTIDE SEQUENCE, STRAIN=J51
Navarro L., Saenz Y., Rojo B., Zarazaga M., Ruiz-Larrea F., Torres C.
"Genetic characterization of the pln locus in the bacteriocin-producer Lactobacillus plantarum strain J51 of wine origin.", Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.

Protein sequence

........10 ........20 ........30 ........40 ........50
| | | | |
MDKFEKISTS NLEKISGGDL TTKLWSSWGY YLGKKARWNL KHPYVQF

Wheel representation

Protein sequence annotations

Feature	Position(s)	Length	Description
CHAIN	1↔29	29	plantaricin NC8 alpha peptide. Feature identifier = PRO_5000063926.
NON_TER	29

Composition

Amino acid	Count	Percent
A	1	2.13 %
C	0	0.00 %
D	2	4.26 %
E	2	4.26 %
F	2	4.26 %
G	4	8.51 %
H	1	2.13 %
I	2	4.26 %
K	7	14.89 %
L	5	10.64 %
M	1	2.13 %
N	2	4.26 %
P	1	2.13 %
Q	1	2.13 %
R	1	2.13 %
S	5	10.64 %
T	3	6.38 %
V	1	2.13 %
W	3	6.38 %
Y	3	6.38 %

Hydrophobicity

Composition

Formula	C₂₅₈ H₃₈₉ N₆₅ O₇₀ S₁
Absent amino acids	C
Common amino acids	K
Mass (Da)	5572.14
Net charge	+5
Isoelectric point	10.19
Basic residues	9
Acidic residues	4
Hydrophobic residues	14
Polar residues	17
Aliphatic residues	8
Tiny residues	10
Boman Index	-74.09
Hydropathy Index	-0.72
Aliphatic Index	66.38
Instability Index	21.92 (stable)
Half Life	Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour
Extinction Coefficient	20970 M^-1 cm^-1
Absorbance 280nm	455.87