Bacteriocin: bavaricin-MN
Accession: BAC067
Classification
Class: class IIA/YGNGV
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Lactobacillus sakei [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Lactobacillales
Lactobacillaceae
Lactobacillus
Target organismsListeria monocytogenes Scott A-
Uniprot and PDB links
UniProt Entry: P80493
PDB EntryUnknown
PROTEIN SEQUENCE, STRAIN=MN
MEDLINE=97111988;PubMed=8953724;
Kaiser A.L., Montville T.J.
"Purification of the bacteriocin bavaricin MN and characterization of its mode of action against Listeria monocytogenes Scott A cells and lipid vesicles.", Appl. Environ. Microbiol. 62:4529-4535(1996).
MEDLINE=97111988;PubMed=8953724;
Kaiser A.L., Montville T.J.
"Purification of the bacteriocin bavaricin MN and characterization of its mode of action against Listeria monocytogenes Scott A cells and lipid vesicles.", Appl. Environ. Microbiol. 62:4529-4535(1996).
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Protein sequence
| ........10 ........20 ........30 ........40 ........50 | | | | | TKYYGNGVYC NSKKCWVDWG QAAGGIGQTV VXGWLGGAIP GK |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| PEPTIDE | 1↔42 | 42 | Bacteriocin bavaricin-MN. Feature identifier = PRO_0000110574. |
| DISULFID | 10↔15 | 6 | By similarity. |
| UNSURE | 10 | ||
| UNSURE | 15 |
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 3 | 7.14 % |
| C | 2 | 4.76 % |
| D | 1 | 2.38 % |
| E | 0 | 0.00 % |
| F | 0 | 0.00 % |
| G | 10 | 23.81 % |
| H | 0 | 0.00 % |
| I | 2 | 4.76 % |
| K | 4 | 9.52 % |
| L | 1 | 2.38 % |
| M | 0 | 0.00 % |
| N | 2 | 4.76 % |
| P | 1 | 2.38 % |
| Q | 2 | 4.76 % |
| R | 0 | 0.00 % |
| S | 1 | 2.38 % |
| T | 2 | 4.76 % |
| V | 4 | 9.52 % |
| W | 3 | 7.14 % |
| Y | 3 | 7.14 % |
Hydrophobicity
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.

Composition
| Formula | C195
H288
N52
O53
S2 |
| Absent amino acids | EFHMR |
| Common amino acids | G |
| Mass (Da) | 4401.59 |
| Net charge | +3 |
| Isoelectric point | 9.25 |
| Basic residues | 4 |
| Acidic residues | 1 |
| Hydrophobic residues | 13 |
| Polar residues | 20 |
| Aliphatic residues | 7 |
| Tiny residues | 14 |
| Boman Index | -8.94 |
| Hydropathy Index | -0.18 |
| Aliphatic Index | 62.62 |
| Instability Index | 5.38 (stable) |
| Half Life |
Mammalian : 7.2 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 21095 M-1 cm-1 |
| Absorbance 280nm | 514.51 |
