Bacteriocin: bavaricin-A
Accession: BAC064
Classification
Class: class IIA/YGNGV
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Lactobacillus sakei [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLactobacillaceaeLactobacillus
Target organismsLactobacillus - Listeria monocytogenes - Pediococcus - Enterococcus - Leuconostoc - Lactococcus
Description
Mode of action:
heat stable bacteriocin.
heat stable bacteriocin.
Uniprot and PDB links
UniProt Entry: P80953
PDB EntryUnknown
PROTEIN SEQUENCE, STRAIN=Bavaricus / MI401
MEDLINE=94012314;PubMed=8407671;
Larsen A.G., Vogensen F.K., Josephsen J.
"Antimicrobial activity of lactic acid bacteria isolated from sour doughs: purification and characterization of bavaricin A, a bacteriocin produced by Lactobacillus bavaricus MI401.", J. Appl. Bacteriol. 75:113-122(1993).
MEDLINE=94012314;PubMed=8407671;
Larsen A.G., Vogensen F.K., Josephsen J.
"Antimicrobial activity of lactic acid bacteria isolated from sour doughs: purification and characterization of bavaricin A, a bacteriocin produced by Lactobacillus bavaricus MI401.", J. Appl. Bacteriol. 75:113-122(1993).
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Protein sequence
| ........10 ........20 ........30 ........40 ........50 | | | | | KYYGNGVHXG KHSXTVDWGT AIGNIGNNAA ANXATGXNAG G |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| PEPTIDE | 1↔41 | 41 | Bacteriocin bavaricin-A. Feature identifier = PRO_0000110573. |
| UNSURE | 1 | K or D. | |
| UNSURE | 41 | G or N. |
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 6 | 14.63 % |
| C | 0 | 0.00 % |
| D | 1 | 2.44 % |
| E | 0 | 0.00 % |
| F | 0 | 0.00 % |
| G | 9 | 21.95 % |
| H | 2 | 4.88 % |
| I | 2 | 4.88 % |
| K | 2 | 4.88 % |
| L | 0 | 0.00 % |
| M | 0 | 0.00 % |
| N | 6 | 14.63 % |
| P | 0 | 0.00 % |
| Q | 0 | 0.00 % |
| R | 0 | 0.00 % |
| S | 1 | 2.44 % |
| T | 3 | 7.32 % |
| V | 2 | 4.88 % |
| W | 1 | 2.44 % |
| Y | 2 | 4.88 % |
Hydrophobicity
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
warning: X is not a standard amino acid.
Composition
| Formula | C154
H224
N50
O48
|
| Absent amino acids | CEFLMPQR |
| Common amino acids | G |
| Mass (Da) | 4002.48 |
| Net charge | +3 |
| Isoelectric point | 9.13 |
| Basic residues | 4 |
| Acidic residues | 1 |
| Hydrophobic residues | 11 |
| Polar residues | 21 |
| Aliphatic residues | 4 |
| Tiny residues | 16 |
| Boman Index | -40.8 |
| Hydropathy Index | -0.5 |
| Aliphatic Index | 47.8 |
| Instability Index | 0.19 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 8480 M-1 cm-1 |
| Absorbance 280nm | 212 |