Bacteriocin: mesentericin Y105
Accession: BAC061
Classification
Class: class IIA/YGNGV
Genetics
Gene: mesY
Producer and target organisms
Producer Organism: Leuconostoc mesenteroides [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLeuconostoc
Target organismsLactobacillus - Leuconostoc - Pediococcus - Listeria monocytogenes - Listeria innocua - Listeria ivanovii
Uniprot and PDB links
UniProt Entry: P38577
PDB EntryUnknown
NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=Y105
MEDLINE=96004463;PubMed=7551032;
Fremaux C., Hechard A., Cenatiempo Y.
"Mesentericin Y105 gene clusters in Leuconostoc mesenteroides Y105.", Microbiology 141:1637-1645(1995).
MEDLINE=96004463;PubMed=7551032;
Fremaux C., Hechard A., Cenatiempo Y.
"Mesentericin Y105 gene clusters in Leuconostoc mesenteroides Y105.", Microbiology 141:1637-1645(1995).
PROTEIN SEQUENCE OF 25-60, STRAIN=Y105
MEDLINE=93139768;PubMed=1487737;
Hechard Y., Derijard B., Letellier F., Cenatiempo Y.
"Characterization and purification of mesentericin Y105, an anti- Listeria bacteriocin from Leuconostoc mesenteroides.", J. Gen. Microbiol. 138:2725-2731(1992).
MEDLINE=93139768;PubMed=1487737;
Hechard Y., Derijard B., Letellier F., Cenatiempo Y.
"Characterization and purification of mesentericin Y105, an anti- Listeria bacteriocin from Leuconostoc mesenteroides.", J. Gen. Microbiol. 138:2725-2731(1992).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene220 | mesI | complement(199..540) | |
| BACGene221 | mesY | complement(561..746) | |
| BACGene222 | mesC | 901..1314 | |
| BACGene223 | mesD | 1361..3529 | |
| BACGene224 | mesE | 3539..4912 |
Protein sequence
| ........10 ........20 ........30 ........40 | | | | KYYGNGVHCT KSGCSVNWGE AASAGIHRLA NGGNGFW |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔37 | 37 | Bacteriocin mesentericin Y105. Feature identifier = PRO_0000002744. |
| DISULFID | 9↔14 | 6 | Probable. |
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 4 | 10.81 % |
| C | 2 | 5.41 % |
| D | 0 | 0.00 % |
| E | 1 | 2.70 % |
| F | 1 | 2.70 % |
| G | 8 | 21.62 % |
| H | 2 | 5.41 % |
| I | 1 | 2.70 % |
| K | 2 | 5.41 % |
| L | 1 | 2.70 % |
| M | 0 | 0.00 % |
| N | 4 | 10.81 % |
| P | 0 | 0.00 % |
| Q | 0 | 0.00 % |
| R | 1 | 2.70 % |
| S | 3 | 8.11 % |
| T | 1 | 2.70 % |
| V | 2 | 5.41 % |
| W | 2 | 5.41 % |
| Y | 2 | 5.41 % |
Hydrophobicity
Composition
| Formula | C169
H246
N52
O50
S2 |
| Absent amino acids | DMPQ |
| Common amino acids | G |
| Mass (Da) | 3888.87 |
| Net charge | +4 |
| Isoelectric point | 8.77 |
| Basic residues | 5 |
| Acidic residues | 1 |
| Hydrophobic residues | 11 |
| Polar residues | 20 |
| Aliphatic residues | 4 |
| Tiny residues | 15 |
| Boman Index | -38.88 |
| Hydropathy Index | -0.41 |
| Aliphatic Index | 47.57 |
| Instability Index | -0.46 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 14105 M-1 cm-1 |
| Absorbance 280nm | 391.81 |