Bacteriocin: Plantaricin C19
Accession: BAC056
Classification
Class: Class IIa
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Lactobacillus plantarum [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Lactobacillales
Lactobacillaceae
Lactobacillus
Description
The sequence of residues 1–36 of plantaricin C19 is determined. Although calculated molecular weight of this sequence is 3750, mass spectrometry analysis revealed a molecular weight of 3845.3.Authors suggest presence of 37 amino acids, the last amino acid corresponding probably to valine. Note=Ref2.
Mode of action:
Plantaricin C19 exerts a bacteriostatic action on sensitive cells of Listeria grayi IP 6818 in BHI broth.
Mode of action:
Plantaricin C19 exerts a bacteriostatic action on sensitive cells of Listeria grayi IP 6818 in BHI broth.
Uniprot and PDB links
UniProt Entry: Q7M173
PDB EntryUnknown
Protein sequence
| ........10 ........20 ........30 ........40 | | | | KYYGNGLSCS KKGCTVNWGQ AFSCGVNRVA TAGHGK |
Wheel representation
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 3 | 8.33 % |
| C | 3 | 8.33 % |
| D | 0 | 0.00 % |
| E | 0 | 0.00 % |
| F | 1 | 2.78 % |
| G | 7 | 19.44 % |
| H | 1 | 2.78 % |
| I | 0 | 0.00 % |
| K | 4 | 11.11 % |
| L | 1 | 2.78 % |
| M | 0 | 0.00 % |
| N | 3 | 8.33 % |
| P | 0 | 0.00 % |
| Q | 1 | 2.78 % |
| R | 1 | 2.78 % |
| S | 3 | 8.33 % |
| T | 2 | 5.56 % |
| V | 3 | 8.33 % |
| W | 1 | 2.78 % |
| Y | 2 | 5.56 % |
Hydrophobicity
Composition
| Formula | C161
H250
N50
O48
S3 |
| Absent amino acids | DEIMP |
| Common amino acids | G |
| Mass (Da) | 3768.84 |
| Net charge | +6 |
| Isoelectric point | 9.87 |
| Basic residues | 6 |
| Acidic residues | 0 |
| Hydrophobic residues | 9 |
| Polar residues | 20 |
| Aliphatic residues | 4 |
| Tiny residues | 13 |
| Boman Index | -44.66 |
| Hydropathy Index | -0.43 |
| Aliphatic Index | 43.33 |
| Instability Index | 18.07 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 8605 M-1 cm-1 |
| Absorbance 280nm | 245.86 |
