Bacteriocin: Divergicin 750
Accession: BAC051
Classification
Class: Unclassified
Genetics
Gene: dvn750
Producer and target organisms
Producer Organism: Carnobacterium divergens [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Lactobacillales
Carnobacteriaceae
Carnobacterium
Target organismsCarnobacterium - Enterococcus - Listeria monocytogenes - Clostridium perfringens
Uniprot and PDB links
UniProt Entry: Q46597
PDB EntryUnknown
NUCLEOTIDE SEQUENCE, STRAIN=750
MEDLINE=97023140;PubMed=8869500;DOI=10.1016/0378-1097(95)00500-5
Holck A.L., Axelsson L.T., Schillinger U.
"Divergicin 750, a novel bacteriocin produced by Carnobacterium divergens 750.", FEMS Microbiol. Lett. 136:163-168(1996).
MEDLINE=97023140;PubMed=8869500;DOI=10.1016/0378-1097(95)00500-5
Holck A.L., Axelsson L.T., Schillinger U.
"Divergicin 750, a novel bacteriocin produced by Carnobacterium divergens 750.", FEMS Microbiol. Lett. 136:163-168(1996).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene183 | dvn750 | divergicin 750 bacteriocin | 53..244 |
| BACGene184 | dvn750 | ORF1 unknown | 494..1063 |
| BACGene185 | dvnT | ABC exporter | 1197..2212 |
Protein sequence
| ........10 ........20 ........30 ........40 | | | | KGILGKLGVV QAGVDFVSGV WAGIKQSAKD HPNA |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔34 | 34 | bacteriocin. Feature identifier = PRO_5000147650. |
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 4 | 11.76 % |
| C | 0 | 0.00 % |
| D | 2 | 5.88 % |
| E | 0 | 0.00 % |
| F | 1 | 2.94 % |
| G | 6 | 17.65 % |
| H | 1 | 2.94 % |
| I | 2 | 5.88 % |
| K | 4 | 11.76 % |
| L | 2 | 5.88 % |
| M | 0 | 0.00 % |
| N | 1 | 2.94 % |
| P | 1 | 2.94 % |
| Q | 2 | 5.88 % |
| R | 0 | 0.00 % |
| S | 2 | 5.88 % |
| T | 0 | 0.00 % |
| V | 5 | 14.71 % |
| W | 1 | 2.94 % |
| Y | 0 | 0.00 % |
Hydrophobicity
Composition
| Formula | C156
H252
N44
O44
|
| Absent amino acids | CEMRTY |
| Common amino acids | G |
| Mass (Da) | 3466.58 |
| Net charge | +3 |
| Isoelectric point | 10.33 |
| Basic residues | 5 |
| Acidic residues | 2 |
| Hydrophobic residues | 15 |
| Polar residues | 9 |
| Aliphatic residues | 9 |
| Tiny residues | 12 |
| Boman Index | -10.75 |
| Hydropathy Index | 0.14 |
| Aliphatic Index | 100.29 |
| Instability Index | 8.37 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 5500 M-1 cm-1 |
| Absorbance 280nm | 166.67 |
