Bacteriocin: Plantaricin S α
Accession: BAC036
Classification
Class: NULL
Genetics
Gene: plsA
Producer and target organisms
Producer Organism: Lactobacillus plantarum [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLactobacillaceaeLactobacillus
Target organismsEnterococcus - Lactobacillus - Lactococcus - Leuconostoc
Description
NULL
Uniprot and PDB links
UniProt Entry: O32831
PDB Entry6GNZ resolved by NMR
NUCLEOTIDE SEQUENCE, STRAIN=LPCO10
MEDLINE=98247325;PubMed=9572965;
Stephens S.K., Floriano B., Cathcart D.P., Bayley S.A., Witt V.F., Jimenez-Diaz R., Warner P.J., Ruiz-Barba J.L.
"Molecular analysis of the genes encoding Plantaricin S, a two-peptide bacteriocin produced by Lactobacillus plantarum LPCO10.", Appl. Environ. Microbiol. 64:1871-1877(1998).
MEDLINE=98247325;PubMed=9572965;
Stephens S.K., Floriano B., Cathcart D.P., Bayley S.A., Witt V.F., Jimenez-Diaz R., Warner P.J., Ruiz-Barba J.L.
"Molecular analysis of the genes encoding Plantaricin S, a two-peptide bacteriocin produced by Lactobacillus plantarum LPCO10.", Appl. Environ. Microbiol. 64:1871-1877(1998).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene135 | plsB | plantaricin S beta protein | 503..646 |
| BACGene136 | plsA | plantaricin S alpha protein | 789..956 |
| BACGene137 | plsK | histidine kinase putative | 2564..3844 |
| BACGene138 | plsR | response regulator protein | 3837..4598 |
Protein sequence
| ........10 ........20 ........30 | | | RNKLAYNMGH YAGKATIFGL AAWALLA |
Wheel representation
3D Structure
View PDB entry: 6GNZ
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔27 | 27 | plantaricin S alpha protein. Feature identifier = PRO_5000147235.
|
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 7 | 25.93 % |
| C | 0 | 0.00 % |
| D | 0 | 0.00 % |
| E | 0 | 0.00 % |
| F | 1 | 3.70 % |
| G | 3 | 11.11 % |
| H | 1 | 3.70 % |
| I | 1 | 3.70 % |
| K | 2 | 7.41 % |
| L | 4 | 14.81 % |
| M | 1 | 3.70 % |
| N | 2 | 7.41 % |
| P | 0 | 0.00 % |
| Q | 0 | 0.00 % |
| R | 1 | 3.70 % |
| S | 0 | 0.00 % |
| T | 1 | 3.70 % |
| V | 0 | 0.00 % |
| W | 1 | 3.70 % |
| Y | 2 | 7.41 % |
Hydrophobicity
Composition
| Formula | C136
H209
N37
O33
S1 |
| Absent amino acids | CDEPQSV |
| Common amino acids | A |
| Mass (Da) | 2940.92 |
| Net charge | +4 |
| Isoelectric point | 10.45 |
| Basic residues | 4 |
| Acidic residues | 0 |
| Hydrophobic residues | 14 |
| Polar residues | 8 |
| Aliphatic residues | 5 |
| Tiny residues | 10 |
| Boman Index | 0.94 |
| Hydropathy Index | 0.34 |
| Aliphatic Index | 98.15 |
| Instability Index | 36.16 (stable) |
| Half Life |
Mammalian : 1 hour Yeast : 2 min E. coli : 2 min |
| Extinction Coefficient | 8480 M-1 cm-1 |
| Absorbance 280nm | 326.15 |