Bacteriocin: Bacteriocin J46
Accession: BAC033
Classification
Class: Unclassified
Genetics
Gene: Bacteriocin J46
Producer and target organisms
Producer Organism: Lactococcus lactis [Gram-positive]
Taxonomy: Bacteria
Firmicutes
Lactobacillales
Streptococcaceae
Lactococcus
Target organismslactobacilli - lactococci - bacilli - clostridia - Streptococcus thermophilus - Clostridium tyrobutyricum
Uniprot and PDB links
UniProt Entry: P71449
PDB EntryUnknown
[Ref. 1]
NUCLEOTIDE SEQUENCE, STRAIN=J46
Huot E., Meghrous J., Barrena-Gonzalez C., Petitdemange H.
"Bacteriocin J46, a new bacteriocin produced by Lactococcus lactis subsp. cremoris J46 : isolation and characterization of the protein and its gene.", Anaerobe 2:137-145(1996).
Huot E., Meghrous J., Barrena-Gonzalez C., Petitdemange H.
"Bacteriocin J46, a new bacteriocin produced by Lactococcus lactis subsp. cremoris J46 : isolation and characterization of the protein and its gene.", Anaerobe 2:137-145(1996).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene122 | lcp J | bacteriocin J46 | 145..300 |
Protein sequence
| ........10 ........20 ........30 | | | KGGSGVIHTI SHEVIYNSWN FVFTCCS |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔27 | 27 | Potential. Feature identifier = PRO_5000146562. |
Composition
| Amino acid | Count | Percent |
|---|---|---|
| A | 0 | 0.00 % |
| C | 2 | 7.41 % |
| D | 0 | 0.00 % |
| E | 1 | 3.70 % |
| F | 2 | 7.41 % |
| G | 3 | 11.11 % |
| H | 2 | 7.41 % |
| I | 3 | 11.11 % |
| K | 1 | 3.70 % |
| L | 0 | 0.00 % |
| M | 0 | 0.00 % |
| N | 2 | 7.41 % |
| P | 0 | 0.00 % |
| Q | 0 | 0.00 % |
| R | 0 | 0.00 % |
| S | 4 | 14.81 % |
| T | 2 | 7.41 % |
| V | 3 | 11.11 % |
| W | 1 | 3.70 % |
| Y | 1 | 3.70 % |
Hydrophobicity
Composition
| Formula | C134
H197
N35
O39
S2 |
| Absent amino acids | ADLMPQR |
| Common amino acids | S |
| Mass (Da) | 3004.8 |
| Net charge | +2 |
| Isoelectric point | 7.41 |
| Basic residues | 3 |
| Acidic residues | 1 |
| Hydrophobic residues | 9 |
| Polar residues | 14 |
| Aliphatic residues | 6 |
| Tiny residues | 7 |
| Boman Index | -13.29 |
| Hydropathy Index | 0.29 |
| Aliphatic Index | 75.56 |
| Instability Index | 11.84 (stable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 7115 M-1 cm-1 |
| Absorbance 280nm | 273.65 |
