Carnocin UI49

Accession: BAC001

Default view

Bacteriocin: carnocin UI49

Accession: BAC001
Classification
Class: lantibiotic
Genetics
Gene: Unidentified
Producer and target organisms

Producer Organism: Carnobacterium sp (strain UI49) [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesCarnobacteriaceaeCarnobacterium

Target organismsCarnobacteria - Lactobacilli - Pediococci - Lactococci

Description
Mode of action:
Lanthionine-containing peptide antibiotic (lantibiotic). Active on Gram-positive bacteria.
Uniprot and PDB links

UniProt Entry: P36960

PDB EntryUnknown

[Ref. 1] | View abstract | Export citation
NULL
MEDLINE=92321768;PubMed=1622206;
Stoffels G., Nissen-Meyer J., Gudmundsdottir A., Sletten K., Holo H., Nes I.F.
"Purification and characterization of a new bacteriocin isolated from a Carnobacterium sp.", Appl Environ Microbiol 58 (5):1417-22(1992).
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Protein sequence
 ........10 
          | 
 GSEIQPR

Warning: partial sequence.
Wheel representation
wheel representation of carnocin UI49
Protein sequence annotations
Features of carnocin UI49


FeaturePosition(s)LengthDescription
PEPTIDE1
Lantibiotic carnocin-UI49.
Feature identifier = PRO_0000045088.
NON_TER7
Composition
Amino acidCountPercent
A00.00 %
C00.00 %
D00.00 %
E114.29 %
F00.00 %
G114.29 %
H00.00 %
I114.29 %
K00.00 %
L00.00 %
M00.00 %
N00.00 %
P114.29 %
Q114.29 %
R114.29 %
S114.29 %
T00.00 %
V00.00 %
W00.00 %
Y00.00 %
Hydrophobicity

Composition
Formula C32 H55 N11 O12
Absent amino acids ACDFHKLMNTVWY
Common amino acids EGIPQRS
Mass (Da) 803.95
Net charge 0
Isoelectric point 6.41
Basic residues 1
Acidic residues 1
Hydrophobic residues 1
Polar residues 2
Aliphatic residues 1
Tiny residues 2
Boman Index -24.81
Hydropathy Index -1.4
Aliphatic Index 55.71
Instability Index 80.34 (unstable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 0 M-1 cm-1
Absorbance 280nm 0