Bacteriocins phylogeny
Bacteriocins are a diverse group of bacterial antimicrobial peptides!
Bacteriocins mechanism of action
Bacteriocin Production: a Probiotic Trait?
Mechanisms via which bacteriocin production could contribute to probiotic functionality. Bacteriocins may act as colonizing peptides, facilitating the competition of a probiotic with the resident microbiota (23); they may function as killing peptides, directly eliminating pathogens (9); or they may serve as signaling peptides, signaling other bacteria or the immune system (32, 40, 56).
Bacteriocins are efficient inhibitor of Clostridium difficile
Transmission electron micrographs of Clostridium difficile ATCC 630 treated for 1 min with :
(a) no inhibitor;
(b) nisin A (16 µg.mL-1);
(c) nisin Z (64 µg.mL-1);
(d) vancomycin (5 µg.mL-1);
(e) nisin A (32 µg.mL-1)
(f) nisin Z (128 µg.mL-1)
(a) no inhibitor;
(b) nisin A (16 µg.mL-1);
(c) nisin Z (64 µg.mL-1);
(d) vancomycin (5 µg.mL-1);
(e) nisin A (32 µg.mL-1)
(f) nisin Z (128 µg.mL-1)
