Bacteriocin: Pentocin KCA1
Accession: BAC224
Classification
Class: Cyclic bacteriocin (Class V)
Genetics
Gene: KCA1_0433
Producer and target organisms
Producer Organism: Lactobacillus pentosus KCA1 [Gram-positive]
Taxonomy: Bacteria
FirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus
Target organismsUnavailable data
Description
Pentocin A is a mature putative circular bacteriocin consisting of alpha-helical structures and has a high proportion of basic amino acid residues.
Uniprot and PDB links
UniProt Entry: I9APR2
PDB EntryUnknown
NUCLEOTIDE SEQUENCE, STRAIN=KCA1.
PubMed=23527145;
Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B., van Hijum S.A., Siezen R.J.
"Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a Healthy Premenopausal Woman.", PLoS ONE 8:E59239-E59239(2013).
PubMed=23527145;
Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B., van Hijum S.A., Siezen R.J.
"Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a Healthy Premenopausal Woman.", PLoS ONE 8:E59239-E59239(2013).
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Protein sequence
| ........10 ........20 ........30 ........40 ........50 ........60 | | | | | | IVWLANKFGV HLTNHLTNSI LNAVSNGSSL GSAFAVIAGV TLPGWAVAAV GALGATAA |
Wheel representation
Composition
Hydrophobicity
Composition
| Formula | C0
H0
N0
O0
S0 |
| Absent amino acids | CDEMQRY |
| Common amino acids | A |
| Mass (Da) | 5 |
| Net charge | +3 |
| Isoelectric point | 9.7 |
| Basic residues | 3 |
| Acidic residues | 0 |
| Hydrophobic residues | 33 |
| Polar residues | 21 |
| Aliphatic residues | 17 |
| Tiny residues | 24 |
| Boman Index | 41.05 |
| Hydropathy Index | 0.964 |
| Aliphatic Index | 122.93 |
| Instability Index | 10.44 (stable) |
| Half Life |
Mammalian : 20 hour Yeast : 30 min E. coli : >10 hour |
| Extinction Coefficient | 11000 M-1 cm-1 |
| Absorbance 280nm | 192.98 |
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