Bacteriocin: Pentocin KCA1

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Bacteriocin: Pentocin KCA1

Accession: BAC224

Classification
Genetics
Gene: KCA1_0433
Producer and target organisms

Producer Organism: Lactobacillus pentosus KCA1 [Gram-positive]

Taxonomy: BacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Target organismsUnavailable data

Description
Pentocin A is a mature putative circular bacteriocin consisting of alpha-helical structures and has a high proportion of basic amino acid residues.
Uniprot and PDB links

UniProt Entry: I9APR2

PDB EntryUnknown

NUCLEOTIDE SEQUENCE, STRAIN=KCA1.
PubMed=23527145;
Anukam K.C., Macklaim J.M., Gloor G.B., Reid G., Boekhorst J., Renckens B., van Hijum S.A., Siezen R.J.
"Genome Sequence of Lactobacillus pentosus KCA1: Vaginal Isolate from a Healthy Premenopausal Woman.", PLoS ONE 8:E59239-E59239(2013).
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Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 
          |          |          |          |          |          | 
 IVWLANKFGV HLTNHLTNSI LNAVSNGSSL GSAFAVIAGV TLPGWAVAAV GALGATAA

Wheel representation
wheel representation of Pentocin KCA1
Composition
Hydrophobicity

Composition
Formula C0 H0 N0 O0 S0
Absent amino acids CDEMQRY
Common amino acids A
Mass (Da) 5
Net charge +3
Isoelectric point 9.7
Basic residues 3
Acidic residues 0
Hydrophobic residues 33
Polar residues 21
Aliphatic residues 17
Tiny residues 24
Boman Index 41.05
Hydropathy Index 0.964
Aliphatic Index 122.93
Instability Index 10.44 (stable)
Half Life Mammalian : 20 hour
Yeast : 30 min
E. coli : >10 hour
Extinction Coefficient 11000 M-1 cm-1
Absorbance 280nm 192.98

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