Bacteriocin: Bactofencin A

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Bacteriocin: Bactofencin A

Accession: BAC221

Classification

Class: ~~Unclassified~~

Genetics

Gene: bfnA

Producer and target organisms

Producer Organism: Lactobacillus salivarius DPC6502 [Gram-positive]

Taxonomy: BacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Target organismslactobacilli - Staphylococcus aureus - Listeria innocua

Uniprot and PDB links

UniProt Entry: V6DMD2

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE.
PubMed=24526652;DOI=10.1128/genomeA.01231-13
Mackenzie D.A., McLay K., Roos S., Walter J., Swarbreck D., Drou N., Crossman L.C., Juge N.
"Draft Genome Sequence of a Novel Lactobacillus salivarius Strain Isolated from Piglet.", Genome Announc. 2:e01231-e01213(2014).

[Ref. 2] | View abstract | Export citation

SEQUENCE AND ACTIVITY.
PubMed=24169573;DOI=10.1128/mBio.00498-13
O'Shea E.F., O'Connor P.M., O'Sullivan O., Cotter P.D., Ross R.P., Hill C.
"Bactofencin A, a new type of cationic bacteriocin with unusual immunity", MBio. 4(6):e00498-13 (2013).

Protein sequence

........10 ........20 ........30
| | |
KRKKHRCRVY NNGMPTGMYR WC

Wheel representation

Composition

Hydrophobicity

Composition

Formula	C₀ H₀ N₀ O₀ S₀
Absent amino acids	ADEFILQS
Common amino acids	R
Mass (Da)	2782.69
Net charge	+8
Isoelectric point	11.12
Basic residues	8
Acidic residues	0
Hydrophobic residues	2
Polar residues	9
Aliphatic residues	1
Tiny residues	2
Boman Index	-81.61
Hydropathy Index	-1.523
Aliphatic Index	13.18
Instability Index	59.33 (unstable)
Half Life	Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min
Extinction Coefficient	8605 M^-1 cm^-1
Absorbance 280nm	409.76

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