Bacteriocin: Bactofencin A

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Bacteriocin: Bactofencin A

Accession: BAC221

Classification
Class: Unclassified
Genetics
Gene: bfnA
Uniprot and PDB links

UniProt Entry: V6DMD2

PDB EntryUnknown

NUCLEOTIDE SEQUENCE.
PubMed=24526652;DOI=10.1128/genomeA.01231-13
Mackenzie D.A., McLay K., Roos S., Walter J., Swarbreck D., Drou N., Crossman L.C., Juge N.
"Draft Genome Sequence of a Novel Lactobacillus salivarius Strain Isolated from Piglet.", Genome Announc. 2:e01231-e01213(2014).
SEQUENCE AND ACTIVITY.
PubMed=24169573;DOI=10.1128/mBio.00498-13
O'Shea E.F., O'Connor P.M., O'Sullivan O., Cotter P.D., Ross R.P., Hill C.
"Bactofencin A, a new type of cationic bacteriocin with unusual immunity", MBio. 4(6):e00498-13 (2013).
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Protein sequence
 ........10 ........20 ........30 
          |          |          | 
 KRKKHRCRVY NNGMPTGMYR WC

Wheel representation
wheel representation of Bactofencin A
Composition
Hydrophobicity

Composition
Formula C0 H0 N0 O0 S0
Absent amino acids ADEFILQS
Common amino acids R
Mass (Da) 2782.69
Net charge +8
Isoelectric point 11.12
Basic residues 8
Acidic residues 0
Hydrophobic residues 2
Polar residues 9
Aliphatic residues 1
Tiny residues 2
Boman Index -81.61
Hydropathy Index -1.523
Aliphatic Index 13.18
Instability Index 59.33 (unstable)
Half Life Mammalian : 1.3 hour
Yeast : 3 min
E. coli : 2 min
Extinction Coefficient 8605 M-1 cm-1
Absorbance 280nm 409.76

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