Bacteriocin: bacteriocin L-1077
Accession: BAC208
Producer Organism: Lactobacillus salivarius L-1077 (NRRL B-50053) [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Lactobacillaceae
Lactobacillus
Target organismsSalmonella Enteritidis 1 (MIC=0.19µg/ml) - Salmonella Enteritidis 4 (MIC=0.38µg/ml) - Salmonella Enteritidis 204 (MIC=0.38µg/ml) - Salmonella Enteritidis 237 (MIC=0.19µg/ml) - Salmonella Choleraesuis 434/4 (MIC=0.38µg/ml) - Salmonella Choleraesuis 370 (MIC=0.19µg/ml) - Salmonella Typhimurium 483/6 (MIC=0.19µg/ml) - Salmonella Typhimurium 44/8 (MIC=0.19µg/ml) - Salmonella Gallinarum-Pullorum Salmonella Gallinarum-Pullorum (MIC=0.19µg/ml) - Escherichia coli HB 101 (MIC=0.19µg/ml) - Escherichia coli-600 (MIC=0.19µg/ml) - Escherichia coli O157:H7 Y-63 (MIC=0.19µg/ml) - Escherichia coli O157:H7 G-35 (MIC=0.19µg/ml) - Escherichia coli O157:H7 OD 30 (MIC=0.19µg/ml) - Escherichia coli O157:H7 T lab 39 (MIC=0.19µg/ml) - Yersinia enterocolitica 03 (MIC=0.76µg/ml) - Yersinia enterocolitica 09 (MIC=0.76µg/ml) - Yersinia enterocolitica 11 (MIC=0.76µg/ml) - Citrobacter freundii (MIC=0.76µg/ml) - Klebsiella pneumoniae (MIC=0.76µg/ml) - Shigella dysenteriae (MIC=0.76µg/ml) - Staphylococcus aureus (MIC=0.76µg/ml) - Staphylococcus epidermidis (MIC=0.76µg/ml) - Yersinia pseudotuberculosis 4 (MIC=0.76µg/ml) - Yersinia pseudotuberculosis 99/14 (MIC=0.76µg/ml) - Pseudomonas aeruginosa 508 (MIC=0.38µg/ml) - Proteus mirabilis (MIC=0.38µg/ml) - Morganella morganii (MIC=0.38µg/ml) - Listeria monocytogenes A 9-72 (MIC=0.19µg/ml) - Proteus vulgaris 7A (MIC=1.5µg/ml) - Clostridium perfringens 13124 (MIC=0.7µg/ml) - Campylobacter jejuni L-4 (MIC=0.09µg/ml)
UniProt Entry: No entry found
PDB EntryUnknown
PubMed=21378051;DOI=10.1128/AEM.02481-10
Svetoch E.A., Eruslanov B.V., Levchuk V.P., Perelygin V.V., Mitsevich E.V., Mitsevich I.P., Stepanshin J., Dyatlov I., Seal B.S., Stern N.J.
"Isolation of Lactobacillus salivarius 1077 (NRRL B-50053) and characterization of its bacteriocin, including the antimicrobial activity spectrum.", Appl Environ Microbiol. 77(8):2749-54 (2011).
........10 ........20 ........30 ........40 | | | | TNYGNGVGVP DAIMAGIIKL IFIFNIRQGY NFGKKAT |
Formula | C0
H0
N0
O0
S0 |
Absent amino acids | CEHSW |
Common amino acids | IG |
Mass (Da) | 4 |
Net charge | +3 |
Isoelectric point | 10.33 |
Basic residues | 4 |
Acidic residues | 1 |
Hydrophobic residues | 15 |
Polar residues | 14 |
Aliphatic residues | 9 |
Tiny residues | 9 |
Boman Index | -12.93 |
Hydropathy Index | 0.262 |
Aliphatic Index | 97.57 |
Instability Index | 2.77 (stable) |
Half Life |
Mammalian : 7.2 hour Yeast : >20 hour E. coli : >10 hour |
Extinction Coefficient | 2980 M-1 cm-1 |
Absorbance 280nm | 82.78 |
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