Bacteriocin: Plantaricin ASM1

Default view

Bacteriocin: Plantaricin ASM1

Accession: BAC185

Classification
Class: Unclassified
Genetics
Gene: bactA1
Producer and target organisms

Producer Organism: Lactobacillus plantarum [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organismsUnavailable data

Description
FUNCTION: Bacteriocin with a narrow antibacterial spectrum. Antibacterial activity against the Gram-positive bacteria
L.plantarun, L.pentosus, L.curvatus, L.lindneri, L.mesenteroides and E.faecilis. Lacks antibacterial activity against the Gram-positive bacteria L.brevis, L.sakei, L. lactis, P.acidilactici, B. subtilis, B. cereus, L. monocytogenes and S.aureus, and against the Gram-negative bacteria E.coli and S.typhimurium.

BIOPHYSICOCHEMICAL PROPERTIES:
pH dependence:Stable from pH 5.5-8.5
Temperature dependence: Thermostable, activity is retained after incubation at 90degrees Celsius for 15 minutes

SUBCELLULAR LOCATION: Secreted.

PTM: Contains 2 disulfide bonds (Probable).

MASS SPECTROMETRY: Mass=5045.72; Method=MALDI; Range=22-64;
NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 22-63, FUNCTION, BIOPHYSICOCHEMICAL PROPERTIES, SUBCELLULAR LOCATION, DISULFIDE BONDS, AND MASS SPECTROMETRY, STRAIN=A-1.
PubMed=19939484;DOI=10.1016/j.ijfoodmicro.2009.10.021
Hata T., Tanaka R., Ohmomo S.
"Isolation and characterization of plantaricin ASM1: a new bacteriocin produced by Lactobacillus plantarum A-1.", Int. J. Food Microbiol. 137:94-99(2010).
Loading...
End Note
Reference Manager
BibTeX
Gene structure
genome of Plantaricin ASM1

Gene idNameDescriptionLocation
BACGene852hypothetical protein352..828
BACGene853hypothetical protein692..775
BACGene854hypothetical protein788..1636
BACGene855hypothetical protein1518..1625
BACGene856bactA1bacteriocin A11718..1912
BACGene857bactA1hypothetical protein1749..1874
bactA1bactA1
Protein sequence
 ........10 ........20 ........30 ........40 ........50 
          |          |          |          |          | 
 KPAWCWYTLA MCGAGYDSGT CDYMYSHCFG VKHSSGGGGS YHC

Wheel representation
wheel representation of Plantaricin ASM1
3D Structure
Protein sequence annotations
Features of Plantaricin ASM1


FeaturePosition(s)LengthDescription
CHAIN1↔4343
Bacteriocin plantarican ASM1.
Feature identifier = PRO_0000394801.
Cross-link40↔434Lanthionine (Ser-Cys) (Probable).
Composition
Hydrophobicity

Composition
Formula C0 H0 N0 O0 S0
Absent amino acids EINQR
Common amino acids G
Mass (Da) 4
Net charge +3
Isoelectric point 7.34
Basic residues 5
Acidic residues 2
Hydrophobic residues 8
Polar residues 25
Aliphatic residues 2
Tiny residues 16
Boman Index -24.71
Hydropathy Index -0.242
Aliphatic Index 22.79
Instability Index 55.58 (unstable)
Half Life Mammalian : 1.3 hour
Yeast : 3 min
E. coli : 2 min
Extinction Coefficient 18700 M-1 cm-1
Absorbance 280nm 445.24

Users comments for Plantaricin ASM1

No comments found

Login or register to submit a comment for Plantaricin ASM1.