Bacteriocin: Leucocin N
Accession: BAC179
Producer Organism: Leuconostoc pseudomesenteroides QU 15 [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLeuconostoc
Target organismsBacillus circulans JCM 2504T (5.20 µmol/l) - Listeria innocua ATCC 33090 (1.30 µmol/l) - Listeria monocytogenes ATCC BAA-679 (1.30 µmol/l) - Enterococcus faecalis JCM 5803 (5.20 µmol/l) - Lactobacillus plantarum ATCC 14917 (2.60 µmol/l) - Lactobacillus sakei ssp. sakei JCM 1157 (1.30 µmol/l) - Leuconostoc mesenteroides ssp. mesenteroides JCM 6124 (2.60 µmol/l) -
Note: not active against Bacillus coagulans JCM 2257 - Bacillus subtilis JCM 1465T - Kocuria rhizophila NBRC 12708 - Lactococcus lactis ssp. lactis ATCC 19435 - Pediococcus pentosaceus JCM 5885
UniProt Entry: D7UPI9
PDB EntryUnknown
PubMed=20070442;DOI=10.1111/j.1365-2672.2009.04653.x
Sawa N, Okamura K, Zendo T, Himeno K, Nakayama J, Sonomoto K.
"Identification and characterization of novel multiple bacteriocins produced by Leuconostoc pseudomesenteroides QU 15", Journal of Applied Microbiology (2010).
| Gene id | Name | Description | Location |
| BACGene832 | LccQ | leucocin Q | 34..195 |
| BACGene833 | LccN | leucocin N | 223..396 |
| ........10 ........20 ........30 ........40 | | | | KGLGKLIGID WLLGQAKDAV KQYKKDYKRW H |
| Formula | C0
H0
N0
O0
S0 |
| Absent amino acids | CEFMNPST |
| Common amino acids | K |
| Mass (Da) | 3 |
| Net charge | +6 |
| Isoelectric point | 10.55 |
| Basic residues | 9 |
| Acidic residues | 3 |
| Hydrophobic residues | 11 |
| Polar residues | 6 |
| Aliphatic residues | 7 |
| Tiny residues | 6 |
| Boman Index | -50.35 |
| Hydropathy Index | -0.855 |
| Aliphatic Index | 91.29 |
| Instability Index | 43.61 (unstable) |
| Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
| Extinction Coefficient | 13980 M-1 cm-1 |
| Absorbance 280nm | 466 |
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