Bacteriocin: Microcin-24
Accession: BAC176
Classification
Class: Unclassified
Genetics
Gene: mtfS
Producer and target organisms
Producer Organism: Escherichia coli [Gram-negative]
Taxonomy: BacteriaProteobacteria
Gammaproteobacteria
Enterobacteriales
Enterobacteriaceae
Escherichia
Target organismsUnavailable data
Description
Channel-forming bacteriocin
Uniprot and PDB links
UniProt Entry: Q46971
PDB EntryUnknown
[Ref. 1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].STRAIN=2424;
O'Brien G.J., Mahanty H.K.
"Complete nucleotide sequence of microcin 24 genetic region andanalysis of a new ABC transporter.", Submitted (JAN-1996) to the EMBL/GenBank/DDBJ database
O'Brien G.J., Mahanty H.K.
"Complete nucleotide sequence of microcin 24 genetic region andanalysis of a new ABC transporter.", Submitted (JAN-1996) to the EMBL/GenBank/DDBJ database
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Gene structure
Gene id | Name | Description | Location |
BACGene815 | mdbA | microcin DNA binding protein | 94..609 |
BACGene816 | mtfI | microcin 24 immunity protein immunity to microcin 24 | 854..1135 |
BACGene817 | mtfS | microcin 24 precursor toxin mcc24 | 1126..1398 |
BACGene818 | mtfA | MtfA microcin 24 transport | 1873..3117 |
BACGene819 | mtfB | MtfB mirocin 24 transport (ABC transporter) | 3107..5230 |
Protein sequence
........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 | | | | | | | | AGDPLADPNS QIVRQIMSNA AWGPPLVPER FRGMAVGAAG GVTQTVLQGA AAHMPVNVPI PKVPMGPSWN GSKG |
Wheel representation
Protein sequence annotations
Feature | Position(s) | Length | Description |
CHAIN | 1↔74 | 74 | Microcin-24. Feature identifier = PRO_0000005678. |
Composition
Hydrophobicity
Composition
Formula | C332
H529
N97
O95
S4 |
Absent amino acids | CY |
Common amino acids | AGP |
Mass (Da) | 7546.94 |
Net charge | +3 |
Isoelectric point | 10.76 |
Basic residues | 6 |
Acidic residues | 3 |
Hydrophobic residues | 27 |
Polar residues | 20 |
Aliphatic residues | 14 |
Tiny residues | 24 |
Boman Index | -45.85 |
Hydropathy Index | -0.03 |
Aliphatic Index | 76.49 |
Instability Index | 36.99 (stable) |
Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
Extinction Coefficient | 11000 M-1 cm-1 |
Absorbance 280nm | 150.68 |
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