Bacteriocin: Durancin TW-49M
Accession: BAC159
Producer Organism: Enterococcus durans QU 49 [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Enterococcaceae
Enterococcus
Target organismsEnterococcus faecalis JCM 5803 - Enterococcus faecium TUA 1344L - Enterococcus hirae ATCC 10541 - Lactobacillus alimentarius JCM 1095 - Lactobacillus kimchii JCM 10707 - Lactobacillus plantarum ATCC 14917 - Lactobacillus sakei ssp. sakei JCM 1157 - Lactococcus lactis ssp. lactis ATCC 19435 - Geobacillus stearothermophilus JCM 2501 - Bacillus subtilis JCM 1465 - Bacillus coagulans JCM 2257 - Bacillus circulans JCM 2504 -
note: not active against Gram-negative bacteria: Enterococcus faecium JCM 5804 - Lactobacillus brevis JCM 1059 - Lactobacillus casei ssp. casei JCM 1134 - Lactobacillus collinoides JCM 1123 - Lactobacillus coryniformis ssp. coryniformis JCM 1164 - Bacillus cereus JCM 2152 - Listeria innocua ATCC 33090 - Micrococcus luteus NBRC 12708 - Escherichia coli JM109
UniProt Entry: B3IUC6
PDB EntryUnknown
Gene id | Name | Description | Location |
BACGene730 | hypothetical protein ORF1 | 1..936 | |
BACGene731 | cda | CDA cytosine deaminase cytosine deaminase homologue | complement(1219..2418) |
BACGene732 | durI | DurI immunity protein of durancin TW-49M | 2555..2827 |
BACGene733 | durM | precursor of durancin TW-49M DurM; non-pediocin-like class II bacteriocin | complement(3019..3237) |
BACGene734 | durF | DurF precursor of durancin TW-49M inducing peptide | 3468..3593 |
BACGene735 | durK | DurK histidine protein kinase homologue | 3636..4931 |
BACGene736 | durR | DurR response regulator homologue | 4942..5688 |
BACGene737 | durT | DurT ABC transporter homologue | 6427..8577 |
BACGene738 | durD | DurD accessory protein homologue | 8595..9959 |
BACGene739 | ims | IMS ImpB/MucB/SamB family protein ImpB/MucB/SamB family protein homologue | 10217..11545 |
BACGene740 | orf11 | hypothetic protein ORF11; hypothetic protein | 11523..11885 |
BACGene741 | ofr12 | hypothetic protein ORF12 | 11976..12155 |
........10 ........20 ........30 ........40 ........50 ........60 | | | | | | ENDHRMPYEL NRPNNLSKGG AKCAAGILGA GLGAVGGGPG GFISAGISAV LGCM |
Formula | C223
H362
N68
O69
S4 |
Absent amino acids | QTW |
Common amino acids | G |
Mass (Da) | 5246.92 |
Net charge | +2 |
Isoelectric point | 8.23 |
Basic residues | 5 |
Acidic residues | 3 |
Hydrophobic residues | 18 |
Polar residues | 23 |
Aliphatic residues | 10 |
Tiny residues | 23 |
Boman Index | -22.27 |
Hydropathy Index | 0.13 |
Aliphatic Index | 81.48 |
Instability Index | 27.86 (stable) |
Half Life |
Mammalian : 1hour Yeast : 30 min E. coli : >10 hour |
Extinction Coefficient | 1490 M-1 cm-1 |
Absorbance 280nm | 30.47 |
Users comments for Durancin TW-49M
No comments found