Bacteriocin: Columbicin A

Default view

Bacteriocin: Columbicin A

Accession: BAC157

Class: Lantibiotic
Gene: colA
Producer and target organisms

Producer Organism: Enterococcus columbae [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus

Target organismsUnavailable data

Uniprot and PDB links

UniProt Entry: A0FL76

PDB EntryUnknown

Martin M., Brede D.A., Herranz C., Nes I.F., Cintas L.M., Hernandez P.E.
""Amino acid and nucleotide sequence of columbicin A, a novel lantibiotic variant produced by Enterococcus columbae PLCH2, isolated from wood pigeons (Columba palumbus)."",
End Note
Reference Manager
Gene structure
genome of Columbicin A

Gene idNameDescriptionLocation
BACGene728colAcolumbicin A class I lantibiotic variant; antimicrobial peptide146..322
BACGene729colAhypothetical protein orfB404..536
Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 
          |          |          |          |          |          | 

Wheel representation
wheel representation of Columbicin A

Formula C263 H435 N71 O86 S7
Absent amino acids HY
Common amino acids IT
Mass (Da) 6211.2
Net charge -2
Isoelectric point 4.39
Basic residues 4
Acidic residues 6
Hydrophobic residues 20
Polar residues 22
Aliphatic residues 13
Tiny residues 13
Boman Index -46.96
Hydropathy Index 0.24
Aliphatic Index 90.86
Instability Index 26.79 (stable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 5500 M-1 cm-1
Absorbance 280nm 100.88

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