Bacteriocin: Columbicin A
Accession: BAC157
Classification
Class: Lantibiotic
Genetics
Gene: colA
Producer and target organisms
Producer Organism: Enterococcus columbae [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Enterococcaceae
Enterococcus
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: A0FL76
PDB EntryUnknown
[Ref. 1]
Martin M., Brede D.A., Herranz C., Nes I.F., Cintas L.M., Hernandez P.E.
""Amino acid and nucleotide sequence of columbicin A, a novel lantibiotic variant produced by Enterococcus columbae PLCH2, isolated from wood pigeons (Columba palumbus)."",
Loading...
Gene structure
Gene id | Name | Description | Location |
BACGene728 | colA | columbicin A class I lantibiotic variant; antimicrobial peptide | 146..322 |
BACGene729 | colA | hypothetical protein orfB | 404..536 |
Protein sequence
........10 ........20 ........30 ........40 ........50 ........60 | | | | | | MMNATENQIF VETVSDQELE MLIGGAGRGW IKTLTKDCPN VISSICAGTI ITACKNCA |
Wheel representation
Composition
Hydrophobicity
Composition
Formula | C263
H435
N71
O86
S7 |
Absent amino acids | HY |
Common amino acids | IT |
Mass (Da) | 6211.2 |
Net charge | -2 |
Isoelectric point | 4.39 |
Basic residues | 4 |
Acidic residues | 6 |
Hydrophobic residues | 20 |
Polar residues | 22 |
Aliphatic residues | 13 |
Tiny residues | 13 |
Boman Index | -46.96 |
Hydropathy Index | 0.24 |
Aliphatic Index | 90.86 |
Instability Index | 26.79 (stable) |
Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
Extinction Coefficient | 5500 M-1 cm-1 |
Absorbance 280nm | 100.88 |
Users comments for Columbicin A
No comments found