Bacteriocin: Nisin F
Accession: BAC146
Classification
Class: Lantibiotic
Genetics
Gene: BacF
Producer and target organisms
Producer Organism: Lactococcus lactis F10 [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Streptococcaceae
Lactococcus
Target organismsStaphylococcus aureus - Staphylococcus carnosus - Lactobacillus curvatus - Lactobacillus plantarum - Lactobacillus reuteri
Description
under review
Uniprot and PDB links
UniProt Entry: A7UGI5
PDB EntryUnknown
GENE SEQUENCEE
PubMed=18039827;DOI=10.1128/AEM.01862-07
de Kwaadsteniet M, Ten Doeschate K, Dicks L M T.
"Characterization of the Structural Gene Encoding Nisin F, a New Lantibiotic Produced by a Lactococcus lactis subsp. lactis Isolate from Freshwater Catfish (Clarias gariepinus)", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2008, 74(2):547-549.
PubMed=18039827;DOI=10.1128/AEM.01862-07
de Kwaadsteniet M, Ten Doeschate K, Dicks L M T.
"Characterization of the Structural Gene Encoding Nisin F, a New Lantibiotic Produced by a Lactococcus lactis subsp. lactis Isolate from Freshwater Catfish (Clarias gariepinus)", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 2008, 74(2):547-549.
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Gene structure
Gene id | Name | Description | Location |
BACGene653 | nisin F | 1..171 |
Protein sequence
........10 ........20 ........30 ........40 | | | | ITSISLCTPG CKTGALMGCN MKTATCNCSV HVSK |
Wheel representation
Composition
Hydrophobicity
Composition
Formula | C140
H243
N41
O46
S7 |
Absent amino acids | DEFQRWY |
Common amino acids | CT |
Mass (Da) | 3479.71 |
Net charge | +4 |
Isoelectric point | 8.51 |
Basic residues | 4 |
Acidic residues | 0 |
Hydrophobic residues | 8 |
Polar residues | 19 |
Aliphatic residues | 6 |
Tiny residues | 9 |
Boman Index | -15.74 |
Hydropathy Index | 0.4 |
Aliphatic Index | 68.82 |
Instability Index | 13.45 (stable) |
Half Life |
Mammalian : 20 hour Yeast : 30 min E. coli : >10 hour |
Extinction Coefficient | 0 M-1 cm-1 |
Absorbance 280nm | 7.58 |
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