Bacteriocin: haloduracin Hal beta
Accession: BAC140
Classification
Class: Lantibiotic (two-peptide)
Genetics
Gene: HalA2
Producer and target organisms
Producer Organism: Bacillus halodurans C-125 [Gram-positive]
Taxonomy: Bacteria
FirmicutesBacillalesBacillaceaeBacillus
Target organismsUnavailable data
Description
under review
Uniprot and PDB links
UniProt Entry: No entry found
PDB EntryUnknown
PROTEIN SEQUENCE
PubMed=17085596;
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
"Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.", Proc Natl Acad Sci U S A. 2006, 103(46):17243-8.
PubMed=17085596;
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
"Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.", Proc Natl Acad Sci U S A. 2006, 103(46):17243-8.
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Protein sequence
| ........10 ........20 ........30 ........40 | | | | GDVHAQTTWP CATVGVSVAL CPTTKCTSQC |
Wheel representation
Composition
Hydrophobicity
Composition
| Formula | C128
H206
N36
O43
S4 |
| Absent amino acids | EFIMNRY |
| Common amino acids | T |
| Mass (Da) | 3084.01 |
| Net charge | +1 |
| Isoelectric point | 7.12 |
| Basic residues | 2 |
| Acidic residues | 1 |
| Hydrophobic residues | 9 |
| Polar residues | 14 |
| Aliphatic residues | 5 |
| Tiny residues | 7 |
| Boman Index | -16.39 |
| Hydropathy Index | 0.257 |
| Aliphatic Index | 10.49 |
| Instability Index | 20.51 (stable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 5750 M-1 cm-1 |
| Absorbance 280nm | 198.28 |
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