Bacteriocin: haloduracin Hal alpha

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Bacteriocin: haloduracin Hal alpha

Accession: BAC139

Classification
Genetics
Gene: HalA1
Producer and target organisms

Producer Organism: Bacillus halodurans C-125 [Gram-positive]

Taxonomy: BacteriaFirmicutesBacillalesBacillaceaeBacillus

Target organismsUnavailable data

Description
under review
Uniprot and PDB links

UniProt Entry: No entry found

PDB EntryUnknown

PROTEIN SEQUENCE
PubMed=17085596;
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
"Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.", Proc Natl Acad Sci U S A. 2006, 103(46):17243-8.
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Protein sequence
 ........10 ........20 ........30 
          |          |          | 
 CAWYNISCRL GNKGAYCTLT VECMPSCN

Wheel representation
wheel representation of haloduracin Hal alpha
Composition
Hydrophobicity

Composition
Formula C130 H202 N36 O40 S6
Absent amino acids DFHQ
Common amino acids C
Mass (Da) 3
Net charge +1
Isoelectric point 7.81
Basic residues 2
Acidic residues 1
Hydrophobic residues 7
Polar residues 16
Aliphatic residues 4
Tiny residues 6
Boman Index -24.04
Hydropathy Index 0.107
Aliphatic Index 59.29
Instability Index 109.53 (unstable)
Half Life Mammalian : 1.2 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 8730 M-1 cm-1
Absorbance 280nm 323.33

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