Bacteriocin: haloduracin Hal alpha
Accession: BAC139
Classification
Class: Lantibiotic (two-peptide)
Genetics
Gene: HalA1
Producer and target organisms
Producer Organism: Bacillus halodurans C-125 [Gram-positive]
Taxonomy: BacteriaFirmicutes
Bacillales
Bacillaceae
Bacillus
Target organismsUnavailable data
Description
under review
Uniprot and PDB links
UniProt Entry: No entry found
PDB EntryUnknown
PROTEIN SEQUENCE
PubMed=17085596;
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
"Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.", Proc Natl Acad Sci U S A. 2006, 103(46):17243-8.
PubMed=17085596;
McClerren AL, Cooper LE, Quan C, Thomas PM, Kelleher NL, van der Donk WA.
"Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic.", Proc Natl Acad Sci U S A. 2006, 103(46):17243-8.
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Protein sequence
........10 ........20 ........30 | | | CAWYNISCRL GNKGAYCTLT VECMPSCN |
Wheel representation
Composition
Hydrophobicity
Composition
Formula | C130
H202
N36
O40
S6 |
Absent amino acids | DFHQ |
Common amino acids | C |
Mass (Da) | 3 |
Net charge | +1 |
Isoelectric point | 7.81 |
Basic residues | 2 |
Acidic residues | 1 |
Hydrophobic residues | 7 |
Polar residues | 16 |
Aliphatic residues | 4 |
Tiny residues | 6 |
Boman Index | -24.04 |
Hydropathy Index | 0.107 |
Aliphatic Index | 59.29 |
Instability Index | 109.53 (unstable) |
Half Life |
Mammalian : 1.2 hour Yeast : >20 hour E. coli : >10 hour |
Extinction Coefficient | 8730 M-1 cm-1 |
Absorbance 280nm | 323.33 |
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