Bacteriocin: Linocin M18

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Bacteriocin: Linocin M18

Accession: BAC137

Classification

Class: ~~Unclassified~~

Genetics

Gene: linM18

Producer and target organisms

Producer Organism: Brevibacterium linens [Gram-positive]

Taxonomy: BacteriaActinobacteriaActinobacteridaeActinomycetalesMicrococcineaeBrevibacteriaceaeBrevibacterium

Target organismslisteria spp

Uniprot and PDB links

UniProt Entry: Q45296

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE, STRAIN=M18;
MEDLINE=97077222;PubMed=8919789;
Valdes-Stauber N., Scherer S.
"Nucleotide sequence and taxonomical distribution of the bacteriocin gene lin cloned from Brevibacterium linens M18.", Appl. Environ. Microbiol. 62:1283-1286(1996).

Gene structure

Gene id	Name	Description	Location
BACGene614	linM18	Linocin M18	14..814

Protein sequence

........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80
| | | | | | | |
MNNLYRELAP IPGPAWAEIE EEARRTFKRN IAGRRIVDVA GPTGFETSAV TTGHIRDVQS ETSGLQVKQR IVQEYIELRT
PFTVTRQAID DVARGSGDSD WQPVKDAATT IAMAEDRAIL HGLDAAGIGG IVPGSSNAAV AIPDAVEDFA DAVAQALSVL
RTVGVDGPYS LLLSSAEYTK VSESTDHGYP IREHLSRQLG AGEIIWAPAL EGALLVSTRG GDYELHLGQD LSIGYYSHDS
ETVELYLQET FGFLA

Protein sequence annotations

Feature	Position(s)	Length	Description
CHAIN	1↔266	266	Linocin-M18. Feature identifier = PRO_0000343953.
CONFLICT	16		W -> A (in Ref. 2; AA sequence).

Composition

Hydrophobicity

Composition

Formula	C₁₂₆₂ H₁₉₈₇ N₃₄₇ O₄₀₇ S₂
Absent amino acids	C
Common amino acids	AL
Mass (Da)	28619.42
Net charge	-13
Isoelectric point	4.39
Basic residues	26
Acidic residues	39
Hydrophobic residues	101
Polar residues	76
Aliphatic residues	58
Tiny residues	72
Boman Index	-395.86
Hydropathy Index	-0.13
Aliphatic Index	-94.66
Instability Index	43.71 (unstable)
Half Life	Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour
Extinction Coefficient	29910 M^-1 cm^-1
Absorbance 280nm	112.87

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