Bacteriocin: Propionicin SM1

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Bacteriocin: Propionicin SM1

Accession: BAC136

Classification
Class: Unclassified
Genetics
Gene: PpnA
Description
Heat-stable protein solated from Swiss raw milk.
Uniprot and PDB links

UniProt Entry: Q9L454

PDB EntryUnknown

NUCLEOTIDE SEQUENCE., STRAIN=DF1.
MEDLINE=20383893;PubMed=10930068;
Miescher S., Stierli M.P., Teuber M., Meile L.
"Propionicin SM1, a bacteriocin from Propionibacterium jensenii DF1: isolation and characterization of the protein and its gene.", Syst. Appl. Microbiol. 23:174-184(2000).
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Gene structure
genome of Propionicin SM1

Gene idNameDescriptionLocation
BACGene604hypothetical protein ORF8155..388
BACGene605hypothetical protein ORF10372..635
BACGene606hypothetical protein ORF9complement(700..1338)
BACGene607putative theta replicase ORF11776..2684
BACGene608hypothetical protein ORF22684..3028
BACGene609hypothetical protein ORF33025..3552
BACGene610Propionicin SM1 PpnA4051..4674
BACGene611hypothetical protein ORF54727..5053
BACGene612putative invertase-like enzyme ORF65212..5757
BACGene613hypothetical protein ORF7complement(5966..6571)
Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 
          |          |          |          |          |          |          |          | 
 MNKTHKMATL VIAAILAAGM TAPTAYADSP GNTRITASEQ SVLTQILGHK PTQTEYNRYV ETYGSVPTEA DINAYIEASE
 SEGSSSQTAA HDDSTSPGTS TEIYTQAAPA RFSMFFLSGT WITRSGVVSL SLKPRKGGIG NEGDERTWKT VYDKFHNAGQ
 WTRYKNNGVD ASMKKQYMCH FKYGMVKTPW NLEPHKKAAD VSPVKCN

Composition
Hydrophobicity

Composition
Formula C995 H1544 N276 O314 S9
Absent amino acids
Common amino acids TAS
Mass (Da) 22706.84
Net charge +9
Isoelectric point 8.94
Basic residues 28
Acidic residues 19
Hydrophobic residues 58
Polar residues 78
Aliphatic residues 28
Tiny residues 55
Boman Index -364.62
Hydropathy Index -0.57
Aliphatic Index 57.58
Instability Index 43.75 (unstable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 37025 M-1 cm-1
Absorbance 280nm 179.73

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