Bacteriocin: lactococcin-G α
Accession: BAC129
Classification
Class: Unclassified
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Lactococcus lactis subsp. lactis (Streptococcus lactis) [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesStreptococcaceaeLactococcus
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: P36961
PDB Entry2JPJ resolved by NMR 2JPL resolved by NMR
PROTEIN SEQUENCE.STRAIN=LMG 2081
MEDLINE=92380946;PubMed=1512201;
Nissen-Meyer J., Holo H., Havarstein L.S., Sletten K., Nes I.F.
"A novel lactococcal bacteriocin whose activity depends on thecomplementary action of two peptides.", J. Bacteriol. 174:5686-5692(1992)
MEDLINE=92380946;PubMed=1512201;
Nissen-Meyer J., Holo H., Havarstein L.S., Sletten K., Nes I.F.
"A novel lactococcal bacteriocin whose activity depends on thecomplementary action of two peptides.", J. Bacteriol. 174:5686-5692(1992)
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Protein sequence
| ........10 ........20 ........30 ........40 | | | | GTWDDIGQGI GRVAYWVGKA MGNMSDVNQA SRINRKKKH |
Wheel representation
3D Structure
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| PEPTIDE | 1↔39 | 39 | Bacteriocin lactococcin-G subunit alpha. Feature identifier = PRO_0000044640. |
| HELIX | 3↔21 | 19 | |
| HELIX | 26↔34 | 9 | |
| HELIX | 35↔37 | 3 |
Composition
Hydrophobicity
Composition
| Formula | C187
H299
N61
O55
S2 |
| Absent amino acids | CEFLP |
| Common amino acids | G |
| Mass (Da) | 4364.59 |
| Net charge | +5 |
| Isoelectric point | 10.84 |
| Basic residues | 8 |
| Acidic residues | 3 |
| Hydrophobic residues | 11 |
| Polar residues | 13 |
| Aliphatic residues | 6 |
| Tiny residues | 11 |
| Boman Index | -90.98 |
| Hydropathy Index | -0.84 |
| Aliphatic Index | 60 |
| Instability Index | 4.44 (stable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 12490 M-1 cm-1 |
| Absorbance 280nm | 328.68 |
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