Bacteriocin: Pyocin S1
Accession: BAC126
Classification
Class: Unclassified
Genetics
Gene: pys1
Producer and target organisms
Producer Organism: Pseudomonas aeruginosa [Gram-negative]
Taxonomy: Bacteria
ProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Target organismsUnavailable data
Description
Causes breakdown of chromosomal DNA as well as complete inhibition of lipid synthesis in sensitive cells.
Uniprot and PDB links
UniProt Entry: Q06583
PDB EntryUnknown
Gene structure
| Gene id | Name | Description | Location |
| BACGene585 | killer protein of pyocin S1 | 370..2226 | |
| BACGene586 | immunity protein of pyocin S1 | 2228..2491 |
Protein sequence
| ........10 ........20 ........30 ........40 ........50 ........60 ........70 ........80 | | | | | | | | MARPIADLIH FNSTTVTASG DVYYGPGGGT GIGPIARPIE HGLDSSTENG WQEFESYADV GVDPRRYVPL QVKEKRREIE LQFRDAEKKL EASVQAELDK ADAALGPAKN LAPLDVINRS LTIVGNALQQ KNQKLLLNQK KITSLGAKNF LTRTAEEIGE QAVREGNING PEAYMRFLDR EMEGLTAAYN VKLFTEAISS LQIRMNTLTA AKASIEAAAA NKAREQAAAE AKRKAEEQAR QQAAIRAANT YAMPANGSVV ATAAGRGLIQ VAQGAASLAQ AISDAIAVLG RVLASAPSVM AVGFASLTYS SRTAEQWQDQ TPDSVRYALG MDAAKLGLPP SVNLNAVAKA SGTVDLPMRL TNEARGNTTT LSVVSTDGVS VPKAVPVRMA AYNATTGLYE VTVPSTTAEA PPLILTWTPA SPPGNQNPSS TTPVVPKPVP VYEGATLTPV KATPETYPGV ITLPEDLIIG FPADSGIKPI YVMFRDPRDV PGAATGKGQP VSGNWLGAAS QGEGAPIPSQ IADKLRGKTF KNWRDFREQF WIAVANDPEL SKQFNPGSLA VMRDGGAPYV RESEQAGGRI KIEIHHKVRV ADGGGVYNMG NLVAVTPKRH IEIHKGGK |
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔617 | 617 | Pyocin-S1. Feature identifier = PRO_0000218685. |
Composition
Hydrophobicity
Composition
| Formula | C2888
H4640
N824
O890
S11 |
| Absent amino acids | C |
| Common amino acids | A |
| Mass (Da) | 65526.8 |
| Net charge | +10 |
| Isoelectric point | 9.3 |
| Basic residues | 72 |
| Acidic residues | 62 |
| Hydrophobic residues | 228 |
| Polar residues | 174 |
| Aliphatic residues | 123 |
| Tiny residues | 175 |
| Boman Index | -900.47 |
| Hydropathy Index | -0.26 |
| Aliphatic Index | 84.07 |
| Instability Index | 39.03 (stable) |
| Half Life |
Mammalian : 4.4 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 56840 M-1 cm-1 |
| Absorbance 280nm | 92.27 |
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