Bacteriocin: Propionicin T1
Accession: BAC123
Classification
Class: Unclassified
Genetics
Gene: pctA
Producer and target organisms
Producer Organism: Propionibacterium thoenii [Gram-positive]
Taxonomy: Bacteria
ActinobacteriaActinobacteridaeActinomycetalesPropionibacterineaePropionibacteriaceaePropionibacterium
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: Q9F6C4
PDB EntryUnknown
NUCLEOTIDE SEQUENCE.
MEDLINE=20466828;PubMed=11010864;DOI=10.1128/AEM.66.10.4230-4236.2000
Faye T., Langsrud T., Nes I.F., Holo H.
"Biochemical and genetic characterization of propionicin T1, a new bacteriocin from Propionibacterium thoenii.", Appl. Environ. Microbiol. 66:4230-4236(2000).
MEDLINE=20466828;PubMed=11010864;DOI=10.1128/AEM.66.10.4230-4236.2000
Faye T., Langsrud T., Nes I.F., Holo H.
"Biochemical and genetic characterization of propionicin T1, a new bacteriocin from Propionibacterium thoenii.", Appl. Environ. Microbiol. 66:4230-4236(2000).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene582 | pctA | propionicin T1 PctA | 292..582 |
| BACGene583 | pctA | putative ABC transporter Orf2 | 647..1921 |
Protein sequence
| ........10 ........20 ........30 ........40 ........50 ........60 ........70 | | | | | | | VPGGCTYTRS NRDVIGTCKT GSGQFRIRLD CNNAPDKTSV WAKPKVMVSV HCLVGQPRSI SFETK |
Wheel representation
Composition
Hydrophobicity
Composition
| Formula | C305
H497
N93
O92
S5 |
| Absent amino acids | - |
| Common amino acids | VGST |
| Mass (Da) | 7118.23 |
| Net charge | +7 |
| Isoelectric point | 10.01 |
| Basic residues | 11 |
| Acidic residues | 4 |
| Hydrophobic residues | 17 |
| Polar residues | 26 |
| Aliphatic residues | 12 |
| Tiny residues | 14 |
| Boman Index | -129.04 |
| Hydropathy Index | -0.386 |
| Aliphatic Index | 3.72 |
| Instability Index | 27.34 (stable) |
| Half Life |
Mammalian : 100 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 7240 M-1 cm-1 |
| Absorbance 280nm | 113.13 |
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