Bacteriocin: Gassericin A

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Bacteriocin: Gassericin A

Accession: BAC121

Classification
Class: Unclassified
Genetics
Gene: gaaA
Producer and target organisms

Producer Organism: Lactobacillus gasseri [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organismsUnavailable data

Uniprot and PDB links

UniProt Entry: O24790

PDB EntryUnknown

NUCLEOTIDE SEQUENCE, STRAIN=LA39
MEDLINE=98312025;PubMed=9648219;
Kawai Y., Saito T., Suzuki M., Itoh T.
"Sequence analysis by cloning of the structural gene of gassericin A, a hydrophobic bacteriocin produced by Lactobacillus gasseri LA39.", Biosci. Biotechnol. Biochem. 62:887-892(1998).
NUCLEOTIDE SEQUENCE
DOI=10.1006/fmic.2001.0412
Kawai, Y., Y. Ishii, K. Uemura, H. Kitazawa, T. Saito, and T. Itoh.
"Lactobacillus reuteri LA6 and Lactobacillus gasseri LA39 isolated from feces of the same human infant produce identical cyclic bacteriocin.", Food Microbiol. 18:407-415 (2001).
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Protein sequence
 ........10 ........20 ........30 ........40 ........50 ........60 
          |          |          |          |          |          | 
 IYWIADQFGI HLATGTARKL LDAMASGASL GTAFAAILGV TLPAWALAAA GALGATAA

Wheel representation
wheel representation of Gassericin A
Composition
Hydrophobicity

Composition
Formula C261 H411 N67 O72 S1
Absent amino acids CEN
Common amino acids A
Mass (Da) 5672.18
Net charge +1
Isoelectric point 7.54
Basic residues 3
Acidic residues 2
Hydrophobic residues 35
Polar residues 15
Aliphatic residues 13
Tiny residues 27
Boman Index 47.31
Hydropathy Index 0.997
Aliphatic Index 31.62
Instability Index 3.73 (stable)
Half Life Mammalian : 20 hour
Yeast : 30 min
E. coli : >10 hour
Extinction Coefficient 19490 M-1 cm-1
Absorbance 280nm 219.12

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