Bacteriocin: Acidocin A
Accession: BAC107
Classification
Class: class IIA/YGNGV
Genetics
Gene: acdA
Producer and target organisms
Producer Organism: Lactobacillus acidophilus [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Lactobacillaceae
Lactobacillus
Target organismsLactobacillus - Streptococcus - Pediococcus - Listeria monocytogenes - Bacillus subtilis - Enterococcus
Uniprot and PDB links
UniProt Entry: Q48496
PDB EntryUnknown
NUCLEOTIDE SEQUENCE, STRAIN=TK9201
MEDLINE=95314239;PubMed=7793908;
Kanatani K., Oshimura M., Sano K.
"Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus.", Appl. Environ. Microbiol. 61:1061-1067(1995).
MEDLINE=95314239;PubMed=7793908;
Kanatani K., Oshimura M., Sano K.
"Isolation and characterization of acidocin A and cloning of the bacteriocin gene from Lactobacillus acidophilus.", Appl. Environ. Microbiol. 61:1061-1067(1995).
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Gene structure
Gene id | Name | Description | Location |
BACGene497 | acdA | acidocin A bacteriocin | 142..387 |
BACGene498 | acdA | ORF2 unknown | 416..583 |
Protein sequence
........10 ........20 ........30 ........40 ........50 ........60 | | | | | | KTYYGTNGVH CTKKSLWGKV RLKNVIPGTL CRKQSLPIKQ DLKILLGWAT GAFGKTFH |
Wheel representation
Protein sequence annotations
Feature | Position(s) | Length | Description |
CHAIN | 1↔58 | 58 | mature acidocin A. Feature identifier = PRO_5000139827. |
Composition
Hydrophobicity
Composition
Formula | C299
H481
N83
O75
S2 |
Absent amino acids | EM |
Common amino acids | K |
Mass (Da) | 6521.72 |
Net charge | +12 |
Isoelectric point | 10.94 |
Basic residues | 13 |
Acidic residues | 1 |
Hydrophobic residues | 19 |
Polar residues | 21 |
Aliphatic residues | 13 |
Tiny residues | 11 |
Boman Index | -59.99 |
Hydropathy Index | -0.3 |
Aliphatic Index | 85.69 |
Instability Index | 23.99 (stable) |
Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
Extinction Coefficient | 14105 M-1 cm-1 |
Absorbance 280nm | 247.46 |
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