Bacteriocin: Plantaricin 423

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Bacteriocin: Plantaricin 423

Accession: BAC104

Classification

Class: class IIa

Genetics

Gene: plaA

Producer and target organisms

Producer Organism: Lactobacillus plantarum [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organisms~~Unavailable data~~

Uniprot and PDB links

UniProt Entry: Q93FV7

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE.
MEDLINE=22311147;PubMed=12423916;DOI=10.1016/S0168-1605(02)00164-2
Van Reenen C.A., Chikindas M.L., Van Zyl W.H., Dicks L.M.
"Characterization and heterologous expression of a class IIa bacteriocin, plantaricin 423 from Lactobacillus plantarum 423, in Saccharomyces cerevisiae.", Int. J. Food Microbiol. 81:29-40(2003).

Gene structure

Gene id	Name	Description	Location
BACGene471	plaA	prebacteriocin 423	400..570
BACGene472	plaB	putative immunity protein	615..944
BACGene473	plaC	accessory protein similar to pedC of pediocin PA-1	1187..1711
BACGene474	plaD	ABC translocator similar to pedD of pediocin PA-1	1810..3984
BACGene475	plaD	RepB	complement(4213..5025)
BACGene476	plaD	mobilization protein	complement(6450..7535)

Protein sequence

........10 ........20 ........30 ........40
| | | |
KYYGNGVTCG KHSCSVNWGQ AFSCSVSHLA NFGHGKC

Wheel representation

Composition

Hydrophobicity

Composition

Formula	C₁₇₀ H₂₄₉ N₅₁ O₅₀ S₄
Absent amino acids	DEIMPR
Common amino acids	G
Mass (Da)	3954.01
Net charge	+6
Isoelectric point	8.67
Basic residues	6
Acidic residues	0
Hydrophobic residues	9
Polar residues	21
Aliphatic residues	4
Tiny residues	13
Boman Index	-36.23
Hydropathy Index	-0.278
Aliphatic Index	6.51
Instability Index	2.68 (stable)
Half Life	Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min
Extinction Coefficient	8730 M^-1 cm^-1
Absorbance 280nm	242.5

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