Bacteriocin: carnobacteriocin-A (Piscicolin-61)
Accession: BAC100
Classification
Genetics
Gene: cbnBA; Synonyms=psc61
Producer and target organisms
Producer Organism: Carnobacterium piscicola [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesCarnobacteriaceaeCarnobacterium
Target organismsCarnobacterium - Enterococcus - Listeria monocytogenes - Clostridium perfringens
Uniprot and PDB links
UniProt Entry: P38578
PDB EntryUnknown
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PARTIAL PROTEIN SEQUENCE, STRAIN=LV17A
MEDLINE=94282297;PubMed=8012574;
Worobo R.W., Henkel T., Sailer M., Roy K.L., Vederas J.C., Stiles M.E.
"Characteristics and genetic determinant of a hydrophobic peptide bacteriocin, carnobacteriocin A, produced by Carnobacterium piscicola LV17A.", Microbiology 140:517-526(1994).
MEDLINE=94282297;PubMed=8012574;
Worobo R.W., Henkel T., Sailer M., Roy K.L., Vederas J.C., Stiles M.E.
"Characteristics and genetic determinant of a hydrophobic peptide bacteriocin, carnobacteriocin A, produced by Carnobacterium piscicola LV17A.", Microbiology 140:517-526(1994).
NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=LV61
MEDLINE=94297487;PubMed=7764997;
Holck A.L., Axelsson L., Schillinger U.
"Purification and cloning of piscicolin 61, a bacteriocin from Carnobacterium piscicola LV61.", Curr. Microbiol. 29:63-68(1994).
MEDLINE=94297487;PubMed=7764997;
Holck A.L., Axelsson L., Schillinger U.
"Purification and cloning of piscicolin 61, a bacteriocin from Carnobacterium piscicola LV61.", Curr. Microbiol. 29:63-68(1994).
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Gene structure
| Gene id | Name | Description | Location |
| BACGene418 | carnobacteriocin A | 334..549 |
Protein sequence
| ........10 ........20 ........30 ........40 ........50 ........60 | | | | | | DQMSDGVNYG KGSSLSKGGA KCGLGIVGGL ATIPSGPLGW LAGAAGVINS CMK |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔53 | 53 | Bacteriocin carnobacteriocin-A. Feature identifier = PRO_0000002761. |
| DISULFID | 22↔51 | 30 |
Composition
Hydrophobicity
Composition
| Formula | C217
H357
N61
O69
S4 |
| Absent amino acids | EFHR |
| Common amino acids | G |
| Mass (Da) | 5071.75 |
| Net charge | +2 |
| Isoelectric point | 8.78 |
| Basic residues | 4 |
| Acidic residues | 2 |
| Hydrophobic residues | 17 |
| Polar residues | 25 |
| Aliphatic residues | 11 |
| Tiny residues | 24 |
| Boman Index | 0.77 |
| Hydropathy Index | 0.26 |
| Aliphatic Index | 84.72 |
| Instability Index | 32.02 (stable) |
| Half Life |
Mammalian : 1.1 hour Yeast : 3 min E. coli : >10 hour |
| Extinction Coefficient | 7115 M-1 cm-1 |
| Absorbance 280nm | 136.83 |
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