Bacteriocin: Plantaricin NC8 α

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Bacteriocin: Plantaricin NC8 α

Accession: BAC089

Classification
Class: Unclassified
Genetics
Gene: plnc8A
Producer and target organisms

Producer Organism: Lactobacillus plantarum [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLactobacillaceaeLactobacillus

Target organismsUnavailable data

NUCLEOTIDE SEQUENCE, STRAIN=NC8
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).
NUCLEOTIDE SEQUENCE, STRAIN=NC8
MEDLINE=22401440;PubMed=12514019;DOI=10.1128/AEM.69.1.383-389.2003
Maldonado A., Ruiz-Barba J.L., Jimenez-Diaz R.
"Purification and genetic characterization of plantaricin NC8, a novel coculture-inducible two-peptide bacteriocin from Lactobacillus plantarum NC8.", Appl. Environ. Microbiol. 69:383-389(2003).
NUCLEOTIDE SEQUENCE, STRAIN=J51
Navarro L., Saenz Y., Rojo B., Zarazaga M., Ruiz-Larrea F., Torres C.
"Genetic characterization of the pln locus in the bacteriocin-producer Lactobacillus plantarum strain J51 of wine origin.", Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
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Protein sequence
 ........10 ........20 ........30 ........40 ........50 
          |          |          |          |          | 
 MDKFEKISTS NLEKISGGDL TTKLWSSWGY YLGKKARWNL KHPYVQF

Wheel representation
wheel representation of Plantaricin NC8 α
Protein sequence annotations
Features of Plantaricin NC8 α


FeaturePosition(s)LengthDescription
CHAIN1↔2929
plantaricin NC8 alpha peptide.
Feature identifier = PRO_5000063926.
NON_TER29
Composition
Hydrophobicity

Composition
Formula C258 H389 N65 O70 S1
Absent amino acids C
Common amino acids K
Mass (Da) 5572.14
Net charge +5
Isoelectric point 10.19
Basic residues 9
Acidic residues 4
Hydrophobic residues 14
Polar residues 17
Aliphatic residues 8
Tiny residues 10
Boman Index -74.09
Hydropathy Index -0.72
Aliphatic Index 66.38
Instability Index 21.92 (stable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 20970 M-1 cm-1
Absorbance 280nm 455.87

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