Bacteriocin: Plantaricin NC8 α
Accession: BAC089
Classification
Class: Unclassified
Genetics
Gene: plnc8A
Producer and target organisms
Producer Organism: Lactobacillus plantarum [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLactobacillaceaeLactobacillus
Target organismsUnavailable data
Uniprot and PDB links
UniProt Entry: Q84HW0
PDB EntryUnknown
NUCLEOTIDE SEQUENCE, STRAIN=NC8
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).
NUCLEOTIDE SEQUENCE, STRAIN=NC8
MEDLINE=22401440;PubMed=12514019;DOI=10.1128/AEM.69.1.383-389.2003
Maldonado A., Ruiz-Barba J.L., Jimenez-Diaz R.
"Purification and genetic characterization of plantaricin NC8, a novel coculture-inducible two-peptide bacteriocin from Lactobacillus plantarum NC8.", Appl. Environ. Microbiol. 69:383-389(2003).
MEDLINE=22401440;PubMed=12514019;DOI=10.1128/AEM.69.1.383-389.2003
Maldonado A., Ruiz-Barba J.L., Jimenez-Diaz R.
"Purification and genetic characterization of plantaricin NC8, a novel coculture-inducible two-peptide bacteriocin from Lactobacillus plantarum NC8.", Appl. Environ. Microbiol. 69:383-389(2003).
[Ref. 3]
NUCLEOTIDE SEQUENCE, STRAIN=J51
Navarro L., Saenz Y., Rojo B., Zarazaga M., Ruiz-Larrea F., Torres C.
"Genetic characterization of the pln locus in the bacteriocin-producer Lactobacillus plantarum strain J51 of wine origin.", Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
Navarro L., Saenz Y., Rojo B., Zarazaga M., Ruiz-Larrea F., Torres C.
"Genetic characterization of the pln locus in the bacteriocin-producer Lactobacillus plantarum strain J51 of wine origin.", Submitted (DEC-2005) to the EMBL/GenBank/DDBJ databases.
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Protein sequence
| ........10 ........20 ........30 ........40 ........50 | | | | | MDKFEKISTS NLEKISGGDL TTKLWSSWGY YLGKKARWNL KHPYVQF |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| CHAIN | 1↔29 | 29 | plantaricin NC8 alpha peptide. Feature identifier = PRO_5000063926. |
| NON_TER | 29 |
Composition
Hydrophobicity
Composition
| Formula | C258
H389
N65
O70
S1 |
| Absent amino acids | C |
| Common amino acids | K |
| Mass (Da) | 5572.14 |
| Net charge | +5 |
| Isoelectric point | 10.19 |
| Basic residues | 9 |
| Acidic residues | 4 |
| Hydrophobic residues | 14 |
| Polar residues | 17 |
| Aliphatic residues | 8 |
| Tiny residues | 10 |
| Boman Index | -74.09 |
| Hydropathy Index | -0.72 |
| Aliphatic Index | 66.38 |
| Instability Index | 21.92 (stable) |
| Half Life |
Mammalian : 30 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 20970 M-1 cm-1 |
| Absorbance 280nm | 455.87 |
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