Bacteriocin: mundticin

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Bacteriocin: mundticin

Accession: BAC073

Classification
Genetics
Gene: Unidentified
Producer and target organisms

Producer Organism: Enterococcus mundtii [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesEnterococcaceaeEnterococcus

Target organismsGram-positive bacteria especially pathogenic Listeria monocytogenes - Clostridium botulinum - Carnobacterium - Enterococcus - Lactobacillus - Leuconostoc - Pediococcus - Listeria innocua -

NOTE:No effect on the growth of a number of yeasts & Gram-negative bacteria.

Description
Mode of action:
pH dependence: Stable from pH 1 to 10; Temperature dependence: Thermostable. Retains 100% of its maximal activity after heating at 100 degrees Celsius for 15 min, but only 50% of activity after heating 1 hour at this same temperature; RANGE=1-43; NOTE=Ref.1.
Uniprot and PDB links

UniProt Entry: P80925

PDB EntryUnknown

PROTEIN SEQUENCE, AND MASS SPECTROMETRY, STRAIN=ATO6
MEDLINE=98405897;PubMed=9733915;DOI=10.1016/S0005-2736(98)00086-8
Bennik M.H.J., Vanloo B., Brasseur R., Gorris L.G.M., Smid E.J.
"A novel bacteriocin with a YGNGV motif from vegetable-associated Enterococcus mundtii: full characterization and interaction with target organisms.", Biochim. Biophys. Acta 1373:47-58(1998).
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BibTeX
Protein sequence
 ........10 ........20 ........30 ........40 ........50 
          |          |          |          |          | 
 KYYGNGVSCN KKGCSVDWGK AIGIIGNNSA ANLATGGAAG WSK

Wheel representation
wheel representation of mundticin
Protein sequence annotations
Features of mundticin


FeaturePosition(s)LengthDescription
PEPTIDE1↔4343
Bacteriocin mundticin.
Feature identifier = PRO_0000110572.
DISULFID9↔146By similarity.
Composition
Hydrophobicity

Composition
Formula C186 H291 N55 O58 S2
Absent amino acids EFHMPQR
Common amino acids G
Mass (Da) 4308.55
Net charge +4
Isoelectric point 9.81
Basic residues 5
Acidic residues 1
Hydrophobic residues 14
Polar residues 23
Aliphatic residues 6
Tiny residues 19
Boman Index -31.82
Hydropathy Index -0.25
Aliphatic Index 63.72
Instability Index 6.27 (stable)
Half Life Mammalian : 1.3 hour
Yeast : 3 min
E. coli : 2 min
Extinction Coefficient 14105 M-1 cm-1
Absorbance 280nm 335.83

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