Bacteriocin: thermophilin A

Default view

Bacteriocin: thermophilin A

Accession: BAC068

Classification
Class: Unclassified
Genetics
Gene: thermophilin A
Uniprot and PDB links

UniProt Entry: O54454

PDB EntryUnknown

NUCLEOTIDE SEQUENCE, STRAIN=SFi13
MEDLINE=97306337;PubMed=9162062;DOI=10.1074/jbc.272.22.14277
Marciset O., Jeronimus-Stratingh M.C., Mollet B., Poolman B.
"Thermophilin 13, a nontypical antilisterial poration complex bacteriocin, that functions without a receptor.", J. Biol. Chem. 272:14277-14284(1997).
Loading...
End Note
Reference Manager
BibTeX
Gene structure
genome of thermophilin A

Gene idNameDescriptionLocation
BACGene239thmAamphipathic pore-forming peptide precursor ThmA79..336
BACGene240thmBenhancer peptide for thermophilin 13 precursor requires ThmB for full activity353..547
BACGene241thermophilin 13 operonunknown hydrophobic peptide537..695
thmAthmBthermophilin 13 operon
Protein sequence
 ........10 ........20 ........30 ........40 ........50 
          |          |          |          |          | 
 GALWGAPAGG VGALPGAFVG AHVGAIAGGF ACMGGMIGNK FN

Wheel representation
wheel representation of thermophilin A
Protein sequence annotations
Features of thermophilin A


FeaturePosition(s)LengthDescription
CHAIN1↔4242
amphipathic pore-forming peptide.
Feature identifier = PRO_5000145345.
Composition
Hydrophobicity

Composition
Formula C173 H262 N48 O45 S3
Absent amino acids DEQRSTY
Common amino acids G
Mass (Da) 3849.21
Net charge +2
Isoelectric point 8.55
Basic residues 2
Acidic residues 0
Hydrophobic residues 20
Polar residues 16
Aliphatic residues 7
Tiny residues 22
Boman Index 54.07
Hydropathy Index 0.87
Aliphatic Index 79.29
Instability Index 37.13 (stable)
Half Life Mammalian : 30 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 5500 M-1 cm-1
Absorbance 280nm 134.15

Users comments for thermophilin A

No comments found

Login or register to submit a comment for thermophilin A.