Bacteriocin: lactococcin MMFII

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Bacteriocin: lactococcin MMFII

Accession: BAC060

Classification
Genetics
Gene: Unidentified
Producer and target organisms
Description
Mode of action:
NOTE=Ref.1.
Uniprot and PDB links

UniProt Entry: P83002

PDB EntryUnknown

PROTEIN SEQUENCE, FUNCTION, AND MASS SPECTROMETRY, STRAIN=MMFII
MEDLINE=21585558;PubMed=11728715;
Ferchichi M., Frere J., Mabrouk K., Manai M.
"Lactococcin MMFII, a novel class IIa bacteriocin produced by Lactococcus lactis MMFII, isolated from a Tunisian dairy product.", FEMS Microbiol. Lett. 205:49-55(2001).
SYNTHESIS, AND 3D-STRUCTURE MODELING, STRAIN=MMFII
MEDLINE=21565876;PubMed=11708769;DOI=10.1006/bbrc.2001.5908
Ferchichi M., Fathallah M., Mansuelle P., Rochat H., Sabatier J.-M., Manai M., Mabrouk K.
"Chemical synthesis, molecular modeling, and antimicrobial activity of a novel bacteriocin, MMFII.", Biochem. Biophys. Res. Commun. 289:13-18(2001).
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Protein sequence
 ........10 ........20 ........30 ........40 
          |          |          |          | 
 TSYGNGVHCN KSKCWIDVSE LETYKAGTVS NPKDILW

Wheel representation
wheel representation of lactococcin MMFII
Protein sequence annotations
Features of lactococcin MMFII


FeaturePosition(s)LengthDescription
PEPTIDE1↔3737
Bacteriocin lactococcin MMFII.
Feature identifier = PRO_0000044637.
DISULFID9↔146
Composition
Hydrophobicity

Composition
Formula C183 H280 N48 O58 S2
Absent amino acids FMQR
Common amino acids KS
Mass (Da) 4163.25
Net charge +1
Isoelectric point 7.25
Basic residues 5
Acidic residues 4
Hydrophobic residues 10
Polar residues 17
Aliphatic residues 7
Tiny residues 8
Boman Index -55.78
Hydropathy Index -0.54
Aliphatic Index 68.38
Instability Index 27.62 (stable)
Half Life Mammalian : 7.2 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 14105 M-1 cm-1
Absorbance 280nm 391.81

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