Bacteriocin: Leucocin-B (Leucocin B-Ta11a)
Accession: BAC059
Classification
Class: class IIA/YGNGV
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Leuconostoc carnosum [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Leuconostoc
Target organismsLactic bacteria - Listeria monocytogenes
Description
Mode of action:
heat stable bacteriocin.
heat stable bacteriocin.
Uniprot and PDB links
UniProt Entry: Q53446
PDB EntryUnknown
NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=Ta11a
MEDLINE=95038272;PubMed=7765496;
Felix J.V., Papathanasopoulos M.A., Smith A.A., von Holy A., Hastings J.W.
"Characterization of leucocin B-Ta11a: a bacteriocin from Leuconostoc carnosum Ta11a isolated from meat.", Curr. Microbiol. 29:207-212(1994).
MEDLINE=95038272;PubMed=7765496;
Felix J.V., Papathanasopoulos M.A., Smith A.A., von Holy A., Hastings J.W.
"Characterization of leucocin B-Ta11a: a bacteriocin from Leuconostoc carnosum Ta11a isolated from meat.", Curr. Microbiol. 29:207-212(1994).
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Gene structure
Gene id | Name | Description | Location |
BACGene218 | leucocin B-Ta11a bacteriocin; precursor | 203..388 | |
BACGene219 | putative immunity protein similar to leucocin A-UAL 187 | 408..749 |
Protein sequence
........10 ........20 ........30 ........40 | | | | KYYGNGVHCT KSGCSVNWGE AFSAGVHRLA NGGNGFW |
Wheel representation
Protein sequence annotations
Feature | Position(s) | Length | Description |
CHAIN | 1↔37 | 37 | Bacteriocin leucocin-B. Feature identifier = PRO_0000002741. |
DISULFID | 9↔14 | 6 | By similarity. |
Composition
Hydrophobicity
Composition
Formula | C174
H248
N52
O50
S2 |
Absent amino acids | DIMPQ |
Common amino acids | G |
Mass (Da) | 3950.93 |
Net charge | +4 |
Isoelectric point | 8.77 |
Basic residues | 5 |
Acidic residues | 1 |
Hydrophobic residues | 11 |
Polar residues | 20 |
Aliphatic residues | 4 |
Tiny residues | 14 |
Boman Index | -38.59 |
Hydropathy Index | -0.39 |
Aliphatic Index | 42.16 |
Instability Index | -1.5 (stable) |
Half Life |
Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min |
Extinction Coefficient | 14105 M-1 cm-1 |
Absorbance 280nm | 391.81 |
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