Bacteriocin: Leucocin-B (Leucocin B-Ta11a)

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Bacteriocin: Leucocin-B (Leucocin B-Ta11a)

Accession: BAC059

Classification

Class: class IIA/YGNGV

Genetics

Gene: ~~Unidentified~~

Producer and target organisms

Producer Organism: Leuconostoc carnosum [Gram-positive]

Taxonomy: BacteriaFirmicutesLactobacillalesLeuconostoc

Target organismsLactic bacteria - Listeria monocytogenes

Description

Mode of action:
heat stable bacteriocin.

Uniprot and PDB links

UniProt Entry: Q53446

PDB Entry~~Unknown~~

[Ref. 1] | View abstract | Export citation

NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=Ta11a
MEDLINE=95038272;PubMed=7765496;
Felix J.V., Papathanasopoulos M.A., Smith A.A., von Holy A., Hastings J.W.
"Characterization of leucocin B-Ta11a: a bacteriocin from Leuconostoc carnosum Ta11a isolated from meat.", Curr. Microbiol. 29:207-212(1994).

Gene structure

Gene id	Name	Description	Location
BACGene218		leucocin B-Ta11a bacteriocin; precursor	203..388
BACGene219		putative immunity protein similar to leucocin A-UAL 187	408..749

Protein sequence

........10 ........20 ........30 ........40
| | | |
KYYGNGVHCT KSGCSVNWGE AFSAGVHRLA NGGNGFW

Wheel representation

Protein sequence annotations

Features of Leucocin-B (Leucocin B-Ta11a)

Feature	Position(s)	Length	Description
CHAIN	1↔37	37	Bacteriocin leucocin-B. Feature identifier = PRO_0000002741.
DISULFID	9↔14	6	By similarity.

Composition

Hydrophobicity

Composition

Formula	C₁₇₄ H₂₄₈ N₅₂ O₅₀ S₂
Absent amino acids	DIMPQ
Common amino acids	G
Mass (Da)	3950.93
Net charge	+4
Isoelectric point	8.77
Basic residues	5
Acidic residues	1
Hydrophobic residues	11
Polar residues	20
Aliphatic residues	4
Tiny residues	14
Boman Index	-38.59
Hydropathy Index	-0.39
Aliphatic Index	42.16
Instability Index	-1.5 (stable)
Half Life	Mammalian : 1.3 hour Yeast : 3 min E. coli : 2 min
Extinction Coefficient	14105 M^-1 cm^-1
Absorbance 280nm	391.81

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