Bacteriocin: Halocin-S8
Accession: BAC055
Classification
Class: Unclassified
Genetics
Gene: halS8
Producer and target organisms
Producer Organism: Haloarchaeon S8a [Gram-]
Taxonomy: ArchaeaEuryarchaeota
Halobacteria
Halobacteriales
Halobacteriaceae
Target organismshaloarchaeons Halobacterium salinarium NRC817 - Halobacterium GRB - Haloferax gibbonsii
Description
Mode of action:
boiled, subjected to organic solvents, and stored at 4 degrees Celsius for extended periods without losing activity.
boiled, subjected to organic solvents, and stored at 4 degrees Celsius for extended periods without losing activity.
Uniprot and PDB links
UniProt Entry: Q9HHA8
PDB EntryUnknown
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 231-266.
MEDLINE=20398181;PubMed=10940040;DOI=10.1128/JB.182.17.4951-4958.2000
Price L.B., Shand R.F.
"Halocin S8: a 36-amino-acid microhalocin from the haloarchaeal strain S8a.", J. Bacteriol. 182:4951-4958(2000).
MEDLINE=20398181;PubMed=10940040;DOI=10.1128/JB.182.17.4951-4958.2000
Price L.B., Shand R.F.
"Halocin S8: a 36-amino-acid microhalocin from the haloarchaeal strain S8a.", J. Bacteriol. 182:4951-4958(2000).
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Gene structure
Gene id | Name | Description | Location |
BACGene196 | halS8 | HalS8 precursor halocin S8; preproprotein | 1095..2030 |
Protein sequence
........10 ........20 ........30 ........40 | | | | SDCNINSNTA ADVILCFNQV GSCALCSPTL VGGPVP |
Wheel representation
Protein sequence annotations
Feature | Position(s) | Length | Description |
PEPTIDE | 1↔36 | 36 | Halocin-S8. Feature identifier = PRO_0000013171. |
PROPEP | 37↔81 | 45 | /FTId=PRO_0000013172. |
Composition
Hydrophobicity
Composition
Formula | C150
H243
N41
O52
S4 |
Absent amino acids | EHKMRWY |
Common amino acids | CNSV |
Mass (Da) | 3599.68 |
Net charge | -2 |
Isoelectric point | 3.49 |
Basic residues | 0 |
Acidic residues | 2 |
Hydrophobic residues | 13 |
Polar residues | 17 |
Aliphatic residues | 9 |
Tiny residues | 10 |
Boman Index | -11.17 |
Hydropathy Index | 0.56 |
Aliphatic Index | 94.72 |
Instability Index | 49.04 (unstable) |
Half Life |
Mammalian : 1.9 hour Yeast : >20 hour E. coli : >10 hour |
Extinction Coefficient | 250 M-1 cm-1 |
Absorbance 280nm | 7.14 |
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