Bacteriocin: Halocin-S8

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Bacteriocin: Halocin-S8

Accession: BAC055

Classification
Class: Unclassified
Genetics
Gene: halS8
Producer and target organisms
Description
Mode of action:
boiled, subjected to organic solvents, and stored at 4 degrees Celsius for extended periods without losing activity.
Uniprot and PDB links

UniProt Entry: Q9HHA8

PDB EntryUnknown

NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND PROTEIN SEQUENCE OF 231-266.
MEDLINE=20398181;PubMed=10940040;DOI=10.1128/JB.182.17.4951-4958.2000
Price L.B., Shand R.F.
"Halocin S8: a 36-amino-acid microhalocin from the haloarchaeal strain S8a.", J. Bacteriol. 182:4951-4958(2000).
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End Note
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BibTeX
Gene structure
genome of Halocin-S8

Gene idNameDescriptionLocation
BACGene196halS8HalS8 precursor halocin S8; preproprotein1095..2030
halS8
Protein sequence
 ........10 ........20 ........30 ........40 
          |          |          |          | 
 SDCNINSNTA ADVILCFNQV GSCALCSPTL VGGPVP

Wheel representation
wheel representation of Halocin-S8
Protein sequence annotations
Features of Halocin-S8


FeaturePosition(s)LengthDescription
PEPTIDE1↔3636
Halocin-S8.
Feature identifier = PRO_0000013171.
PROPEP37↔8145/FTId=PRO_0000013172.
Composition
Hydrophobicity

Composition
Formula C150 H243 N41 O52 S4
Absent amino acids EHKMRWY
Common amino acids CNSV
Mass (Da) 3599.68
Net charge -2
Isoelectric point 3.49
Basic residues 0
Acidic residues 2
Hydrophobic residues 13
Polar residues 17
Aliphatic residues 9
Tiny residues 10
Boman Index -11.17
Hydropathy Index 0.56
Aliphatic Index 94.72
Instability Index 49.04 (unstable)
Half Life Mammalian : 1.9 hour
Yeast : >20 hour
E. coli : >10 hour
Extinction Coefficient 250 M-1 cm-1
Absorbance 280nm 7.14

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