Bacteriocin: plantaricin K
Accession: BAC044
Classification
Class: Unclassified
Genetics
Gene: plnK
Producer and target organisms
Producer Organism: Lactobacillus plantarum [Gram-positive]
Taxonomy: BacteriaFirmicutes
Lactobacillales
Lactobacillaceae
Lactobacillus
Target organismsPediococcus pentosaceus - Lactobacillus plantarum - Lactobacillus casei - Lactobacillus sakei - Lactobacillus viridescens - Pediococcus pentosaceus - Carnobacterium piscicola - Lactobacillus plantarum - Lactobacillus sakei - Pediococcus acidilactici - Lactobacillus curvatus
Uniprot and PDB links
UniProt Entry: P71460
PDB Entry2KEG resolved by NMR. Structure in dpc micelles 2KEH resolved by NMR. (TFE)
NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=C11
MEDLINE=94161498;PubMed=8117074;
Diep B.D., Havarstein L.S., Nissen-Meyer J., Nes F.I.
"The gene encoding plantaricin A, a bacteriocin from Lactobacillus plantarum C11, is located on the same transcription unit as an agr- like regulatory system.", Appl. Environ. Microbiol. 60:160-166(1994).
MEDLINE=94161498;PubMed=8117074;
Diep B.D., Havarstein L.S., Nissen-Meyer J., Nes F.I.
"The gene encoding plantaricin A, a bacteriocin from Lactobacillus plantarum C11, is located on the same transcription unit as an agr- like regulatory system.", Appl. Environ. Microbiol. 60:160-166(1994).
NUCLEOTIDE SEQUENCE [GENOMIC DNA], STRAIN=C11
MEDLINE=96345611;PubMed=8755874;
Diep D.B., Havarstein L.S., Nes I.F.
"Characterization of the locus responsible for the bacteriocin production in Lactobacillus plantarum C11.", J. Bacteriol. 178:4472-4483(1996).
MEDLINE=96345611;PubMed=8755874;
Diep D.B., Havarstein L.S., Nes I.F.
"Characterization of the locus responsible for the bacteriocin production in Lactobacillus plantarum C11.", J. Bacteriol. 178:4472-4483(1996).
NUCLEOTIDE SEQUENCE, STRAIN=C11
MEDLINE=96414465;PubMed=8817486;
Diep D.B., Haavarstein S.L., Nes I.F.
"A bacteriocin-like peptide induces bacteriocin synthesis in Lactobacillus plantarum C11.", Mol. Microbiol. 18:631-639(1995).
MEDLINE=96414465;PubMed=8817486;
Diep D.B., Haavarstein S.L., Nes I.F.
"A bacteriocin-like peptide induces bacteriocin synthesis in Lactobacillus plantarum C11.", Mol. Microbiol. 18:631-639(1995).
NUCLEOTIDE SEQUENCE, STRAIN=NC8
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).
PubMed=14973042;DOI=10.1128/JB.186.5.1556-1564.2004
Maldonado A., Jimenez-Diaz R., Ruiz-Barba J.L.
"Induction of plantaricin production in Lactobacillus plantarum NC8 after coculture with specific gram-positive bacteria is mediated by an autoinduction mechanism.", J. Bacteriol. 186:1556-1564(2004).
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Protein sequence
........10 ........20 ........30 ........40 | | | | RRSRKNGIGY AIGYAFGAVE RAVLGGSRDY NK |
Wheel representation
3D Structure
Protein sequence annotations
Feature | Position(s) | Length | Description |
CHAIN | 1↔32 | 32 | bacteriocin peptide K. Feature identifier = PRO_5000146710. |
CHAIN | 1↔32 | 32 | bacteriocin peptide PlnK. Feature identifier = PRO_5000063929. |
Composition
Hydrophobicity
Composition
Formula | C153
H245
N51
O44
|
Absent amino acids | CHMPQTW |
Common amino acids | G |
Mass (Da) | 3521.46 |
Net charge | +5 |
Isoelectric point | 10.98 |
Basic residues | 7 |
Acidic residues | 2 |
Hydrophobic residues | 10 |
Polar residues | 13 |
Aliphatic residues | 5 |
Tiny residues | 12 |
Boman Index | -83.03 |
Hydropathy Index | -0.66 |
Aliphatic Index | 67.19 |
Instability Index | 64.1 (unstable) |
Half Life |
Mammalian : 1 hour Yeast : 2 min E. coli : 2 min |
Extinction Coefficient | 4470 M-1 cm-1 |
Absorbance 280nm | 144.19 |
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