Bacteriocin: Lichenin

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Bacteriocin: Lichenin

Accession: BAC007

Classification
Class: Unclassified
Genetics
Gene: Unidentified
Producer and target organisms

Producer Organism: Bacillus licheniformis [Gram-positive]

Taxonomy: BacteriaFirmicutesBacillalesBacillaceaeBacillus

Target organismsHas antibacterial activity only against strictly anaerobic rumen bacteria.

Description
Mode of action:
Oxygen labile bacteriocin-like. pH dependence: Optimum pH is 6.8; Temperature dependence: Optimum temperature is 39 degrees Celsius; 72-96 hours of incubation.
Uniprot and PDB links

UniProt Entry: P82907

PDB EntryUnknown

PROTEIN SEQUENCE, STRAIN=26L-10/3RA
MEDLINE=21460732;PubMed=11576300;DOI=10.1046/j.1365-2672.2001.01429.x
Pattnaik P., Kaushik J.K., Grover S., Batish V.K.
"Purification and characterization of a bacteriocin-like compound (Lichenin) produced anaerobically by Bacillus licheniformis isolated from water buffalo.", J. Appl. Microbiol. 91:636-645(2001).
PROTEIN SEQUENCE, STRAIN=26L-10/3RA
Pattnaik P.
"Biochemical characterization and molecular genetics of bacteriocin produced by a selected rumen bacterial isolate.", Thesis (1999), National Dairy Research Institute / Karnal, India.
EXPRESSION, STRAIN=26L-10/3RA
PubMed=15881839;DOI=10.1016/j.micres.2005.01.006
Pattnaik P., Grover S., Batish V.K.
"Effect of environmental factors on production of lichenin, a chromosomally encoded bacteriocin-like compound produced by Bacillus licheniformis 26L-10/3RA.", Microbiol. Res. 160:213-218(2005).
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Protein sequence
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 ISLEICXIFH DN

Wheel representation
wheel representation of Lichenin
Protein sequence annotations
Features of Lichenin


FeaturePosition(s)LengthDescription
PEPTIDE1↔1212
Lichenin.
Feature identifier = PRO_0000044154.
Composition
Hydrophobicity
warning: X is not a standard amino acid. warning: X is not a standard amino acid.

Composition
Formula C58 H88 N14 O17 S1
Absent amino acids AGKMPQRTVWY
Common amino acids I
Mass (Da) 1413.68
Net charge -1
Isoelectric point 4.18
Basic residues 1
Acidic residues 2
Hydrophobic residues 5
Polar residues 3
Aliphatic residues 4
Tiny residues 1
Boman Index -6.29
Hydropathy Index 0.68
Aliphatic Index 130
Instability Index 23.55 (stable)
Half Life Mammalian : 20 hour
Yeast : 30 min
E. coli : >10 hour
Extinction Coefficient 0 M-1 cm-1
Absorbance 280nm 0

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