Bacteriocin: Curvalicin-28a
Accession: BAC005
Classification
Class: Unclassified
Genetics
Gene: Unidentified
Producer and target organisms
Producer Organism: Lactobacillus curvatus [Gram-positive]
Taxonomy: Bacteria
FirmicutesLactobacillalesLactobacillaceaeLactobacillus
Target organismsListeria monocytogenes
Description
Mode of action:
Bacteriocin active against Listeria monocytogenes. RANGE=1-12; NOTE=Ref.1.
Bacteriocin active against Listeria monocytogenes. RANGE=1-12; NOTE=Ref.1.
Uniprot and PDB links
UniProt Entry: P84709
PDB EntryUnknown
PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY, STRAIN=CWBI-B28
PubMed=16680519;DOI=10.1007/s10482-006-9063-0
Ghalfi H., Benkerroum N., Ongena M., Van Beuumen J., Wathelet B., Vandenberghe I., Bensaid M., Thonart P.
"Purification and characterization of three novel plasmid-born bacteriocins (curvalicins 28) produced by Lactobacillus curvatus CWBI- B28.", Antonie Van Leeuwenhoek 96(3):361-361(2009).
PubMed=16680519;DOI=10.1007/s10482-006-9063-0
Ghalfi H., Benkerroum N., Ongena M., Van Beuumen J., Wathelet B., Vandenberghe I., Bensaid M., Thonart P.
"Purification and characterization of three novel plasmid-born bacteriocins (curvalicins 28) produced by Lactobacillus curvatus CWBI- B28.", Antonie Van Leeuwenhoek 96(3):361-361(2009).
[Ref. 2]
PROTEIN SEQUENCE, FUNCTION, SUBCELLULAR LOCATION, AND MASS SPECTROMETRY, STRAIN=CWBI-B28
DOI=10.1016/j.foodres.2009.08.009
Ghalfi H., Benkerroum N., Ongena M., Bensaid M., Thonart P.
"Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.", Food Research International 43(1):33-39 (2010).
DOI=10.1016/j.foodres.2009.08.009
Ghalfi H., Benkerroum N., Ongena M., Bensaid M., Thonart P.
"Production of three anti-listerial peptides by Lactobacillus curvatus in MRS broth.", Food Research International 43(1):33-39 (2010).
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Protein sequence
| ........10 ........20 | | TPVVNPPFLQ QT |
Wheel representation
Protein sequence annotations
| Feature | Position(s) | Length | Description |
| PEPTIDE | 1 | Bioactive peptide 1. Feature identifier = PRO_0000223895. | |
| NON_TER | 12 |
Composition
Hydrophobicity
Composition
| Formula | C62
H97
N15
O18
|
| Absent amino acids | ACDEGHIKMRSWY |
| Common amino acids | P |
| Mass (Da) | 1358.72 |
| Net charge | 0 |
| Isoelectric point | 6.11 |
| Basic residues | 0 |
| Acidic residues | 0 |
| Hydrophobic residues | 4 |
| Polar residues | 3 |
| Aliphatic residues | 3 |
| Tiny residues | 0 |
| Boman Index | -6.88 |
| Hydropathy Index | -0.14 |
| Aliphatic Index | 80.83 |
| Instability Index | 98.13 (unstable) |
| Half Life |
Mammalian : 7.2 hour Yeast : >20 hour E. coli : >10 hour |
| Extinction Coefficient | 0 M-1 cm-1 |
| Absorbance 280nm | 0 |
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